Assessing Public Health and Social Measures Against COVID-19 in Japan From March to June 2021

BackgroundPublic health and social measures (PHSM) against COVID-19 in Japan involve requesting the public to voluntarily reduce social contact; these measures are not legally binding. The effectiveness of such PHSM has been questioned with emergence of the SARS-CoV-2 Alpha variant (B.1.1.7), which...

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Main Authors: Katsuma Hayashi, Taishi Kayano, Asami Anzai, Marie Fujimoto, Natalie Linton, Misaki Sasanami, Ayako Suzuki, Tetsuro Kobayashi, Kanako Otani, Masato Yamauchi, Motoi Suzuki, Hiroshi Nishiura
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.937732/full
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author Katsuma Hayashi
Taishi Kayano
Asami Anzai
Marie Fujimoto
Natalie Linton
Misaki Sasanami
Ayako Suzuki
Tetsuro Kobayashi
Kanako Otani
Masato Yamauchi
Motoi Suzuki
Hiroshi Nishiura
author_facet Katsuma Hayashi
Taishi Kayano
Asami Anzai
Marie Fujimoto
Natalie Linton
Misaki Sasanami
Ayako Suzuki
Tetsuro Kobayashi
Kanako Otani
Masato Yamauchi
Motoi Suzuki
Hiroshi Nishiura
author_sort Katsuma Hayashi
collection DOAJ
description BackgroundPublic health and social measures (PHSM) against COVID-19 in Japan involve requesting the public to voluntarily reduce social contact; these measures are not legally binding. The effectiveness of such PHSM has been questioned with emergence of the SARS-CoV-2 Alpha variant (B.1.1.7), which exhibited elevated transmissibility.Materials and MethodsWe investigated the epidemic dynamics during the fourth epidemic wave in Japan from March to June 2021 involving pre-emergency measures and declaration of a state of emergency (SoE). We estimated the effective reproduction number (Rt) before and after these interventions, and then analyzed the relationship between lower Rt values and each PHSM.ResultsWith implementation of pre-emergency measures (PEM) in 16 prefectures, the Rt was estimated to be < 1 in six prefectures; its average relative reduction ranged from 2 to 19%. During the SoE, 8 of 10 prefectures had an estimated Rt < 1, and the average relative reduction was 26%–39%. No single intervention was identified that uniquely resulted in an Rt value < 1.ConclusionAn SoE can substantially reduce the Rt and may be required to curb a surge in cases caused by future SARS-CoV-2 variants of concern with elevated transmissibility. More customized interventions did not reduce the Rt value to < 1 in this study, but that may be partly attributable to the greater transmissibility of the Alpha variant.
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spelling doaj.art-cf4b63a1b9224f85ada727118ccb057e2022-12-22T01:26:11ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-07-01910.3389/fmed.2022.937732937732Assessing Public Health and Social Measures Against COVID-19 in Japan From March to June 2021Katsuma Hayashi0Taishi Kayano1Asami Anzai2Marie Fujimoto3Natalie Linton4Misaki Sasanami5Ayako Suzuki6Tetsuro Kobayashi7Kanako Otani8Masato Yamauchi9Motoi Suzuki10Hiroshi Nishiura11School of Public Health, Kyoto University, Kyoto, JapanSchool of Public Health, Kyoto University, Kyoto, JapanSchool of Public Health, Kyoto University, Kyoto, JapanSchool of Public Health, Kyoto University, Kyoto, JapanSchool of Public Health, Kyoto University, Kyoto, JapanSchool of Public Health, Kyoto University, Kyoto, JapanSchool of Public Health, Kyoto University, Kyoto, JapanSchool of Public Health, Kyoto University, Kyoto, JapanNational Institute of Infectious Diseases, Tokyo, JapanNational Institute of Infectious Diseases, Tokyo, JapanNational Institute of Infectious Diseases, Tokyo, JapanSchool of Public Health, Kyoto University, Kyoto, JapanBackgroundPublic health and social measures (PHSM) against COVID-19 in Japan involve requesting the public to voluntarily reduce social contact; these measures are not legally binding. The effectiveness of such PHSM has been questioned with emergence of the SARS-CoV-2 Alpha variant (B.1.1.7), which exhibited elevated transmissibility.Materials and MethodsWe investigated the epidemic dynamics during the fourth epidemic wave in Japan from March to June 2021 involving pre-emergency measures and declaration of a state of emergency (SoE). We estimated the effective reproduction number (Rt) before and after these interventions, and then analyzed the relationship between lower Rt values and each PHSM.ResultsWith implementation of pre-emergency measures (PEM) in 16 prefectures, the Rt was estimated to be < 1 in six prefectures; its average relative reduction ranged from 2 to 19%. During the SoE, 8 of 10 prefectures had an estimated Rt < 1, and the average relative reduction was 26%–39%. No single intervention was identified that uniquely resulted in an Rt value < 1.ConclusionAn SoE can substantially reduce the Rt and may be required to curb a surge in cases caused by future SARS-CoV-2 variants of concern with elevated transmissibility. More customized interventions did not reduce the Rt value to < 1 in this study, but that may be partly attributable to the greater transmissibility of the Alpha variant.https://www.frontiersin.org/articles/10.3389/fmed.2022.937732/fullcoronavirusstatistical estimationmodelingInfectious Diseasemathematical modeleffective reproduction number
spellingShingle Katsuma Hayashi
Taishi Kayano
Asami Anzai
Marie Fujimoto
Natalie Linton
Misaki Sasanami
Ayako Suzuki
Tetsuro Kobayashi
Kanako Otani
Masato Yamauchi
Motoi Suzuki
Hiroshi Nishiura
Assessing Public Health and Social Measures Against COVID-19 in Japan From March to June 2021
Frontiers in Medicine
coronavirus
statistical estimation
modeling
Infectious Disease
mathematical model
effective reproduction number
title Assessing Public Health and Social Measures Against COVID-19 in Japan From March to June 2021
title_full Assessing Public Health and Social Measures Against COVID-19 in Japan From March to June 2021
title_fullStr Assessing Public Health and Social Measures Against COVID-19 in Japan From March to June 2021
title_full_unstemmed Assessing Public Health and Social Measures Against COVID-19 in Japan From March to June 2021
title_short Assessing Public Health and Social Measures Against COVID-19 in Japan From March to June 2021
title_sort assessing public health and social measures against covid 19 in japan from march to june 2021
topic coronavirus
statistical estimation
modeling
Infectious Disease
mathematical model
effective reproduction number
url https://www.frontiersin.org/articles/10.3389/fmed.2022.937732/full
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