Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report
Abstract Background Chikungunya virus infection in neonates is relatively rare and can lead to death. Case presentation We report the occurrence of the first death of a mother and child after probable vertical transmission of chikungunya virus in Brazil. A 28-year-old pregnant woman with hypertensio...
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| Format: | Article |
| Language: | English |
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BMC
2018-07-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12879-018-3243-1 |
| _version_ | 1818240531998703616 |
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| author | Rhaquel de Morais Alves Barbosa Oliveira Francisca Kalline de Almeida Barreto Ana Maria Peixoto Cabral Maia Ileana Pitombeira Gomes Adriana Rocha Simião Rebeca Bandeira Barbosa Adilina Soares Romeiro Rodrigues Kilma Wanderley Lopes Fernanda Montenegro de Carvalho Araújo Regina Lúcia Sousa do Vale John Washington Cavalcante Luciano Pamplona de Góes Cavalcanti |
| author_facet | Rhaquel de Morais Alves Barbosa Oliveira Francisca Kalline de Almeida Barreto Ana Maria Peixoto Cabral Maia Ileana Pitombeira Gomes Adriana Rocha Simião Rebeca Bandeira Barbosa Adilina Soares Romeiro Rodrigues Kilma Wanderley Lopes Fernanda Montenegro de Carvalho Araújo Regina Lúcia Sousa do Vale John Washington Cavalcante Luciano Pamplona de Góes Cavalcanti |
| author_sort | Rhaquel de Morais Alves Barbosa Oliveira |
| collection | DOAJ |
| description | Abstract Background Chikungunya virus infection in neonates is relatively rare and can lead to death. Case presentation We report the occurrence of the first death of a mother and child after probable vertical transmission of chikungunya virus in Brazil. A 28-year-old pregnant woman with hypertension presented with symptoms compatible with an arboviral disease at 34 weeks’ gestation. She developed preeclampsia with severe respiratory failure which resulted in the emergency cesarean section, and the patient died 12 days after the onset of symptoms. The pre-term newborn weighed 2535 g, with an Apgar score of 4/8. He was referred to the neonatal ICU with neutrophilia and thrombocytopenia, several seizure episodes, and hemorrhagic disorders, which resulted in death. Chikungunya IgM antibody was detected in the cerebrospinal fluid. Conclusions We present the first documented maternal and neonatal death in Brazil after probable chikungunya infection during pregnancy. |
| first_indexed | 2024-12-12T13:14:56Z |
| format | Article |
| id | doaj.art-cf4dd9c91cf541e2bf799708ce585c53 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-12T13:14:56Z |
| publishDate | 2018-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-cf4dd9c91cf541e2bf799708ce585c532022-12-22T00:23:27ZengBMCBMC Infectious Diseases1471-23342018-07-011811510.1186/s12879-018-3243-1Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case reportRhaquel de Morais Alves Barbosa Oliveira0Francisca Kalline de Almeida Barreto1Ana Maria Peixoto Cabral Maia2Ileana Pitombeira Gomes3Adriana Rocha Simião4Rebeca Bandeira Barbosa5Adilina Soares Romeiro Rodrigues6Kilma Wanderley Lopes7Fernanda Montenegro de Carvalho Araújo8Regina Lúcia Sousa do Vale9John Washington Cavalcante10Luciano Pamplona de Góes Cavalcanti11Collective Health, Federal University of Ceara (UFC)Collective Health, Federal University of Ceara (UFC)Collective Health, Federal University of Ceara (UFC)Collective Health, Federal University of Ceara (UFC)Collective Health, Federal University of Ceara (UFC)Collective Health, Federal University of Ceara (UFC)Collective Health, Federal University of Ceara (UFC)Member of the Investigation Committee for arbovirus deathsMember of the Investigation Committee for arbovirus deathsMember of the Investigation Committee for arbovirus deathsPathology, Federal University of Ceara (UFC)Member of the Investigation Committee for arbovirus deathsAbstract Background Chikungunya virus infection in neonates is relatively rare and can lead to death. Case presentation We report the occurrence of the first death of a mother and child after probable vertical transmission of chikungunya virus in Brazil. A 28-year-old pregnant woman with hypertension presented with symptoms compatible with an arboviral disease at 34 weeks’ gestation. She developed preeclampsia with severe respiratory failure which resulted in the emergency cesarean section, and the patient died 12 days after the onset of symptoms. The pre-term newborn weighed 2535 g, with an Apgar score of 4/8. He was referred to the neonatal ICU with neutrophilia and thrombocytopenia, several seizure episodes, and hemorrhagic disorders, which resulted in death. Chikungunya IgM antibody was detected in the cerebrospinal fluid. Conclusions We present the first documented maternal and neonatal death in Brazil after probable chikungunya infection during pregnancy.http://link.springer.com/article/10.1186/s12879-018-3243-1Chikungunya virusArbovirus infectionDeathsVertical transmission |
| spellingShingle | Rhaquel de Morais Alves Barbosa Oliveira Francisca Kalline de Almeida Barreto Ana Maria Peixoto Cabral Maia Ileana Pitombeira Gomes Adriana Rocha Simião Rebeca Bandeira Barbosa Adilina Soares Romeiro Rodrigues Kilma Wanderley Lopes Fernanda Montenegro de Carvalho Araújo Regina Lúcia Sousa do Vale John Washington Cavalcante Luciano Pamplona de Góes Cavalcanti Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report BMC Infectious Diseases Chikungunya virus Arbovirus infection Deaths Vertical transmission |
| title | Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report |
| title_full | Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report |
| title_fullStr | Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report |
| title_full_unstemmed | Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report |
| title_short | Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report |
| title_sort | maternal and infant death after probable vertical transmission of chikungunya virus in brazil case report |
| topic | Chikungunya virus Arbovirus infection Deaths Vertical transmission |
| url | http://link.springer.com/article/10.1186/s12879-018-3243-1 |
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