Antioxidants: The new frontier for translational research in cerebroprotection
It is important for the anesthesiologist to understand the etiology of free radical damage and how free-radical scavengers attenuate this, so that this knowledge can be applied to diverse neuro-pathological conditions. This review will concentrate on the role of reactive species of oxygen in the pat...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Journal of Anaesthesiology Clinical Pharmacology |
| Subjects: | |
| Online Access: | http://www.joacp.org/article.asp?issn=0970-9185;year=2014;volume=30;issue=2;spage=160;epage=171;aulast=Tewari |
| _version_ | 1818485954411757568 |
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| author | Anurag Tewari Vidhi Mahendru Ashish Sinha Federico Bilotta |
| author_facet | Anurag Tewari Vidhi Mahendru Ashish Sinha Federico Bilotta |
| author_sort | Anurag Tewari |
| collection | DOAJ |
| description | It is important for the anesthesiologist to understand the etiology of free radical damage and how free-radical scavengers attenuate this, so that this knowledge can be applied to diverse neuro-pathological conditions. This review will concentrate on the role of reactive species of oxygen in the pathophysiology of organ dysfunction, specifically sub arachnoid hemorrhage (SAH), traumatic brain injury (TBI) as well as global central nervous system (CNS) hypoxic, ischemic and reperfusion states. We enumerate potential therapeutic modalities that are been currently investigated and of interest for future trials. Antioxidants are perhaps the next frontier of translational research, especially in neuro-anesthesiology. |
| first_indexed | 2024-12-10T16:16:24Z |
| format | Article |
| id | doaj.art-cf4e05c6a61d42ebb3c4f443bd305298 |
| institution | Directory Open Access Journal |
| issn | 0970-9185 |
| language | English |
| last_indexed | 2024-12-10T16:16:24Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Anaesthesiology Clinical Pharmacology |
| spelling | doaj.art-cf4e05c6a61d42ebb3c4f443bd3052982022-12-22T01:41:57ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852014-01-0130216017110.4103/0970-9185.130001Antioxidants: The new frontier for translational research in cerebroprotectionAnurag TewariVidhi MahendruAshish SinhaFederico BilottaIt is important for the anesthesiologist to understand the etiology of free radical damage and how free-radical scavengers attenuate this, so that this knowledge can be applied to diverse neuro-pathological conditions. This review will concentrate on the role of reactive species of oxygen in the pathophysiology of organ dysfunction, specifically sub arachnoid hemorrhage (SAH), traumatic brain injury (TBI) as well as global central nervous system (CNS) hypoxic, ischemic and reperfusion states. We enumerate potential therapeutic modalities that are been currently investigated and of interest for future trials. Antioxidants are perhaps the next frontier of translational research, especially in neuro-anesthesiology.http://www.joacp.org/article.asp?issn=0970-9185;year=2014;volume=30;issue=2;spage=160;epage=171;aulast=TewariAntioxidantscerebroprotectionneuro-anesthesiologyneurocritical care |
| spellingShingle | Anurag Tewari Vidhi Mahendru Ashish Sinha Federico Bilotta Antioxidants: The new frontier for translational research in cerebroprotection Journal of Anaesthesiology Clinical Pharmacology Antioxidants cerebroprotection neuro-anesthesiology neurocritical care |
| title | Antioxidants: The new frontier for translational research in cerebroprotection |
| title_full | Antioxidants: The new frontier for translational research in cerebroprotection |
| title_fullStr | Antioxidants: The new frontier for translational research in cerebroprotection |
| title_full_unstemmed | Antioxidants: The new frontier for translational research in cerebroprotection |
| title_short | Antioxidants: The new frontier for translational research in cerebroprotection |
| title_sort | antioxidants the new frontier for translational research in cerebroprotection |
| topic | Antioxidants cerebroprotection neuro-anesthesiology neurocritical care |
| url | http://www.joacp.org/article.asp?issn=0970-9185;year=2014;volume=30;issue=2;spage=160;epage=171;aulast=Tewari |
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