The Application of Artificial-Intelligence-Assisted Dental Age Assessment in Children with Growth Delay

Background: This study aimed to reveal the efficacy of the artificial intelligence (AI)-assisted dental age (DA) assessment in identifying the characteristics of growth delay (GD) in children. Methods: The panoramic films matching the inclusion criteria were collected for the AI model training to es...

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Main Authors: Te-Ju Wu, Chia-Ling Tsai, Quan-Ze Gao, Yueh-Peng Chen, Chang-Fu Kuo, Ying-Hua Huang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/12/7/1158
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author Te-Ju Wu
Chia-Ling Tsai
Quan-Ze Gao
Yueh-Peng Chen
Chang-Fu Kuo
Ying-Hua Huang
author_facet Te-Ju Wu
Chia-Ling Tsai
Quan-Ze Gao
Yueh-Peng Chen
Chang-Fu Kuo
Ying-Hua Huang
author_sort Te-Ju Wu
collection DOAJ
description Background: This study aimed to reveal the efficacy of the artificial intelligence (AI)-assisted dental age (DA) assessment in identifying the characteristics of growth delay (GD) in children. Methods: The panoramic films matching the inclusion criteria were collected for the AI model training to establish the population-based DA standard. Subsequently, the DA of the validation dataset of the healthy children and the images of the GD children were assessed by both the conventional methods and the AI-assisted standards. The efficacy of all the studied modalities was compared by the paired sample <i>t</i>-test. Results: The AI-assisted standards can provide much more accurate chronological age (CA) predictions with mean errors of less than 0.05 years, while the traditional methods presented overestimated results in both genders. For the GD children, the convolutional neural network (CNN) revealed the delayed DA in GD children of both genders, while the machine learning models presented so only in the GD boys. Conclusion: The AI-assisted DA assessments help overcome the long-standing populational limitation observed in traditional methods. The image feature extraction of the CNN models provided the best efficacy to reveal the nature of delayed DA in GD children of both genders.
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spelling doaj.art-cf4e4b84a13946d09af5486f45817ea12023-11-30T21:15:40ZengMDPI AGJournal of Personalized Medicine2075-44262022-07-01127115810.3390/jpm12071158The Application of Artificial-Intelligence-Assisted Dental Age Assessment in Children with Growth DelayTe-Ju Wu0Chia-Ling Tsai1Quan-Ze Gao2Yueh-Peng Chen3Chang-Fu Kuo4Ying-Hua Huang5Department of Craniofacial Orthodontics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833253, TaiwanDepartment of Pedodontics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833253, TaiwanCenter for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital, Taoyuan 333423, TaiwanCenter for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital, Taoyuan 333423, TaiwanDivision of Rheumatology, Allergy and Immunology, Center for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan 333423, TaiwanDepartment of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833253, TaiwanBackground: This study aimed to reveal the efficacy of the artificial intelligence (AI)-assisted dental age (DA) assessment in identifying the characteristics of growth delay (GD) in children. Methods: The panoramic films matching the inclusion criteria were collected for the AI model training to establish the population-based DA standard. Subsequently, the DA of the validation dataset of the healthy children and the images of the GD children were assessed by both the conventional methods and the AI-assisted standards. The efficacy of all the studied modalities was compared by the paired sample <i>t</i>-test. Results: The AI-assisted standards can provide much more accurate chronological age (CA) predictions with mean errors of less than 0.05 years, while the traditional methods presented overestimated results in both genders. For the GD children, the convolutional neural network (CNN) revealed the delayed DA in GD children of both genders, while the machine learning models presented so only in the GD boys. Conclusion: The AI-assisted DA assessments help overcome the long-standing populational limitation observed in traditional methods. The image feature extraction of the CNN models provided the best efficacy to reveal the nature of delayed DA in GD children of both genders.https://www.mdpi.com/2075-4426/12/7/1158artificial intelligencechronological ageconvolutional neural networkdental ageDemirjian’s methodmachine learning
spellingShingle Te-Ju Wu
Chia-Ling Tsai
Quan-Ze Gao
Yueh-Peng Chen
Chang-Fu Kuo
Ying-Hua Huang
The Application of Artificial-Intelligence-Assisted Dental Age Assessment in Children with Growth Delay
Journal of Personalized Medicine
artificial intelligence
chronological age
convolutional neural network
dental age
Demirjian’s method
machine learning
title The Application of Artificial-Intelligence-Assisted Dental Age Assessment in Children with Growth Delay
title_full The Application of Artificial-Intelligence-Assisted Dental Age Assessment in Children with Growth Delay
title_fullStr The Application of Artificial-Intelligence-Assisted Dental Age Assessment in Children with Growth Delay
title_full_unstemmed The Application of Artificial-Intelligence-Assisted Dental Age Assessment in Children with Growth Delay
title_short The Application of Artificial-Intelligence-Assisted Dental Age Assessment in Children with Growth Delay
title_sort application of artificial intelligence assisted dental age assessment in children with growth delay
topic artificial intelligence
chronological age
convolutional neural network
dental age
Demirjian’s method
machine learning
url https://www.mdpi.com/2075-4426/12/7/1158
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