The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis

The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis

The first line of defense in innate immunity is provided by cellular and humoral mediators. Pentraxins are a superfamily of phylogenetically conserved humoral mediators of innate immunity. PTX3, the first long pentraxin identified, is a soluble pattern recognition molecule rapidly produced by severa...

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Bibliographic Details
Main Authors: Rémi Porte, Sadaf Davoudian, Fatemeh Asgari, Raffaella Parente, Alberto Mantovani, Cecilia Garlanda, Barbara Bottazzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
pentraxin
pentraxin 3 (PTX3)
inflammation
innate immunity
sepsis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00794/full

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