The role of tranexamic acid in breast and body contouring surgery: a review of the literature

**Background**: Postoperative seroma and haematoma are two of the most common complications follow-ing large surface area surgeries. A review of the literature was performed to evaluate evidence for the use of tranexamic acid in reducing postoperative seroma and haematoma formation in breast surgery...

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Main Authors: Daniel Wong, Tai K 'Quoc' Lam
Format: Article
Language:English
Published: Australian Society of Plastic Surgeons 2022-03-01
Series:Australasian Journal of Plastic Surgery
Online Access:https://doi.org/10.34239/ajops.v5n1.277
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author Daniel Wong
Tai K 'Quoc' Lam
author_facet Daniel Wong
Tai K 'Quoc' Lam
author_sort Daniel Wong
collection DOAJ
description **Background**: Postoperative seroma and haematoma are two of the most common complications follow-ing large surface area surgeries. A review of the literature was performed to evaluate evidence for the use of tranexamic acid in reducing postoperative seroma and haematoma formation in breast surgery and body contouring surgery. **Methods**: A literature search was performed using MEDLINE, the Cochrane Database of Systematic Review, the Cochrane Central Register of Controlled Trials (CENTRAL), the Database of Abstracts of Reviews of Ef-fect (DARE) and PubMed in English from 1 Jan 1990–30 Mar 2020. The search terms ‘TXA’, ‘breast reduction’, ‘mammaplasty’, ‘breast implants’, ‘breast implantation’, ‘breast reconstruction’, ‘mastectomy’, ‘tissue ex-pansion’, ‘body contouring’, ‘breast’ and ‘abdominoplasty’ were used alone and in combination. **Results**: A total of six articles were found including three randomised controlled trials, two cohort studies and one retrospective study. Two ongoing trials were found on The Cochrane Central Register of Con-trolled Trials (CENTRAL). No systematic reviews were found. **Conclusion**: Literature surrounding the use of TXA in breast and body contouring surgery is sparse com-pared to what is available in other surgical sub-specialties. The literature available shows promising results with the use of TXA in controlling haematoma, drain output and seroma formation in breast surgery and body contouring surgery with minimal morbidity in these patient groups
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spelling doaj.art-cf53a685cc5b4e1fa218c8aacbae81422024-04-23T16:02:34ZengAustralian Society of Plastic SurgeonsAustralasian Journal of Plastic Surgery2209-170X2022-03-0151The role of tranexamic acid in breast and body contouring surgery: a review of the literatureDaniel WongTai K 'Quoc' Lam**Background**: Postoperative seroma and haematoma are two of the most common complications follow-ing large surface area surgeries. A review of the literature was performed to evaluate evidence for the use of tranexamic acid in reducing postoperative seroma and haematoma formation in breast surgery and body contouring surgery. **Methods**: A literature search was performed using MEDLINE, the Cochrane Database of Systematic Review, the Cochrane Central Register of Controlled Trials (CENTRAL), the Database of Abstracts of Reviews of Ef-fect (DARE) and PubMed in English from 1 Jan 1990–30 Mar 2020. The search terms ‘TXA’, ‘breast reduction’, ‘mammaplasty’, ‘breast implants’, ‘breast implantation’, ‘breast reconstruction’, ‘mastectomy’, ‘tissue ex-pansion’, ‘body contouring’, ‘breast’ and ‘abdominoplasty’ were used alone and in combination. **Results**: A total of six articles were found including three randomised controlled trials, two cohort studies and one retrospective study. Two ongoing trials were found on The Cochrane Central Register of Con-trolled Trials (CENTRAL). No systematic reviews were found. **Conclusion**: Literature surrounding the use of TXA in breast and body contouring surgery is sparse com-pared to what is available in other surgical sub-specialties. The literature available shows promising results with the use of TXA in controlling haematoma, drain output and seroma formation in breast surgery and body contouring surgery with minimal morbidity in these patient groupshttps://doi.org/10.34239/ajops.v5n1.277
spellingShingle Daniel Wong
Tai K 'Quoc' Lam
The role of tranexamic acid in breast and body contouring surgery: a review of the literature
Australasian Journal of Plastic Surgery
title The role of tranexamic acid in breast and body contouring surgery: a review of the literature
title_full The role of tranexamic acid in breast and body contouring surgery: a review of the literature
title_fullStr The role of tranexamic acid in breast and body contouring surgery: a review of the literature
title_full_unstemmed The role of tranexamic acid in breast and body contouring surgery: a review of the literature
title_short The role of tranexamic acid in breast and body contouring surgery: a review of the literature
title_sort role of tranexamic acid in breast and body contouring surgery a review of the literature
url https://doi.org/10.34239/ajops.v5n1.277
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