No Mediation Effect of Telomere Length or Mitochondrial DNA Copy Number on the Association Between Adverse Childhood Experiences (ACEs) and Central Arterial Stiffness

No Mediation Effect of Telomere Length or Mitochondrial DNA Copy Number on the Association Between Adverse Childhood Experiences (ACEs) and Central Arterial Stiffness

Background Adverse childhood experiences (ACEs) have been linked to increased cardiovascular disease (CVD) risk. Previous reports have suggested that accelerated biological aging—indexed by telomere length (TL) and mitochondrial DNA copy number (mtDNAcn)—may contribute to associations between ACEs a...

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Bibliographic Details
Main Authors: Nathaniel J. Iannarelli, Terrance J. Wade, Kylie S. Dempster, Jessy Moore, Adam J. MacNeil, Deborah D. O'Leary
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
adverse childhood experiences
biological aging
central arterial stiffness
mitochondrial DNA copy number
telomere length
vascular aging
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.026619

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