Myeloid-derived suppressor cells in bacterial infections

Myeloid-derived suppressor cells in bacterial infections

Myeloid-derived suppressor cells (MDSCs) comprise monocytic and granulocytic innate immune cells with the capability of suppressing T- and NK-cell responses. While the role of MDSCs has been studied in depth in malignant diseases, the understanding of their regulation and function in infectious dise...

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Bibliographic Details
Main Authors: Michael eOst, Anurag eSingh, Andreas ePeschel, Roman eMehling, Nikolaus eRieber, Dominik eHartl
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Bacteria
Infection
Sepsis
immune suppression
myeloid-derived suppressor cells
MDSC
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00037/full

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