Tumor targeting nanoparticle E749-57-HSP110-RGD elicits potent anti-tumor immune response in a CD8-dependent manner in cervical cancer-bearing mouse model

Tumor targeting nanoparticle E749-57-HSP110-RGD elicits potent anti-tumor immune response in a CD8-dependent manner in cervical cancer-bearing mouse model

Our previous research verified that HSP (heat shock protein) 110 could enhance the anti-tumor effect of HPV16 E749-57 epitope. In this study, to optimize the immunotherapy of this vaccine type, we developed and evaluated the anti-tumor immunity of a nanoparticle vaccine format assembling with E749-5...

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Bibliographic Details
Main Authors: Yue Zhang, Faliang Ren, Bing Ni, Tao Jing, Jun Tang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-10-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
hsp110
nanoparticle vaccine
cervical cancer
hpv16 e7
rgd
Online Access:http://dx.doi.org/10.1080/21645515.2021.1933875

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