Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid Leukemia
Introduction: COVID-19 infection prompts inflammatory responses and acute lung injury in human beings. Complete blood count with differential is essential investigative tool in its managing. However, very few studies revealed the variations of blood cell morphology in this disease. Case report: We r...
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| Format: | Article |
| Language: | English |
| Published: |
West Asia Organization for Cancer Prevention
2021-09-01
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| Series: | Asian Pacific Journal of Cancer Biology |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcb/article/view/713 |
| _version_ | 1797341037273808896 |
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| author | Hedieh Moradi Tabriz Elham Nazar Fatemeh Jazayeri Arezoo Eftekhar Javadi |
| author_facet | Hedieh Moradi Tabriz Elham Nazar Fatemeh Jazayeri Arezoo Eftekhar Javadi |
| author_sort | Hedieh Moradi Tabriz |
| collection | DOAJ |
| description | Introduction: COVID-19 infection prompts inflammatory responses and acute lung injury in human beings. Complete blood count with differential is essential investigative tool in its managing. However, very few studies revealed the variations of blood cell morphology in this disease.
Case report: We reported a 39-years- old female patient complained of respiratory distress one week prior to hospitalization. The patient suffered from cough, fever, and molecular test was reported positive for COVID-19 infection. Laboratory data revealed severe permanent leukopenia and peripheral blood smear examination showed blastoid cells after remission of respiratory signs. Patient underwent bone marrow biopsy for rule out acute myeloid leukemia. But, on bone marrow sample, only viral cytopathic effects were seen. COVID-19 virus stimulates inflammatory cells to produces various inflammatory cytokines and as a result, viral cytopathic effects on white blood cells is seen.
Conclusion: We have described how the characteristic peripheral blood findings of COVID‐19 infection can be misinterpret as acute myeloid leukemia. |
| first_indexed | 2024-03-08T10:12:06Z |
| format | Article |
| id | doaj.art-cf5b27010d744d4fb4315484b867b70a |
| institution | Directory Open Access Journal |
| issn | 2538-4635 |
| language | English |
| last_indexed | 2024-03-08T10:12:06Z |
| publishDate | 2021-09-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Biology |
| spelling | doaj.art-cf5b27010d744d4fb4315484b867b70a2024-01-29T07:28:55ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Biology2538-46352021-09-016323123310.31557/apjcb.2021.6.3.231-233713Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid LeukemiaHedieh Moradi Tabriz0Elham Nazar1Fatemeh Jazayeri2Arezoo Eftekhar Javadi3Department of Pathology, Sina Hospital, Tehran University of Medical Siences, Tehran, Iran.Department of Pathology, Sina Hospital, Tehran University of Medical Siences, Tehran, Iran.Department of Pathology, Sina Hospital, Tehran University of Medical Siences, Tehran, Iran.Department of Pathology, Sina Hospital, Tehran University of Medical Siences, Tehran, Iran.Introduction: COVID-19 infection prompts inflammatory responses and acute lung injury in human beings. Complete blood count with differential is essential investigative tool in its managing. However, very few studies revealed the variations of blood cell morphology in this disease. Case report: We reported a 39-years- old female patient complained of respiratory distress one week prior to hospitalization. The patient suffered from cough, fever, and molecular test was reported positive for COVID-19 infection. Laboratory data revealed severe permanent leukopenia and peripheral blood smear examination showed blastoid cells after remission of respiratory signs. Patient underwent bone marrow biopsy for rule out acute myeloid leukemia. But, on bone marrow sample, only viral cytopathic effects were seen. COVID-19 virus stimulates inflammatory cells to produces various inflammatory cytokines and as a result, viral cytopathic effects on white blood cells is seen. Conclusion: We have described how the characteristic peripheral blood findings of COVID‐19 infection can be misinterpret as acute myeloid leukemia.http://www.waocp.com/journal/index.php/apjcb/article/view/713covid-19, hematology, leukemia |
| spellingShingle | Hedieh Moradi Tabriz Elham Nazar Fatemeh Jazayeri Arezoo Eftekhar Javadi Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid Leukemia Asian Pacific Journal of Cancer Biology covid-19, hematology, leukemia |
| title | Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid Leukemia |
| title_full | Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid Leukemia |
| title_fullStr | Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid Leukemia |
| title_full_unstemmed | Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid Leukemia |
| title_short | Hematologic Presentations of COVID-19 Can be Misinterpreted as Acute Myeloid Leukemia |
| title_sort | hematologic presentations of covid 19 can be misinterpreted as acute myeloid leukemia |
| topic | covid-19, hematology, leukemia |
| url | http://www.waocp.com/journal/index.php/apjcb/article/view/713 |
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