Repertoires of spike avalanches are modulated by behavior and novelty
Neuronal avalanches measured as consecutive bouts of thresholded field potentials represent a statistical signature that the brain operates near a critical point. In theory, criticality optimizes stimulus sensitivity, information transmission, computational capability and mnemonic repertoires size....
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-03-01
|
| Series: | Frontiers in Neural Circuits |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncir.2016.00016/full |
| _version_ | 1818453363177553920 |
|---|---|
| author | Tiago Lins Ribeiro Tiago Lins Ribeiro Sidarta eRibeiro Mauro eCopelli |
| author_facet | Tiago Lins Ribeiro Tiago Lins Ribeiro Sidarta eRibeiro Mauro eCopelli |
| author_sort | Tiago Lins Ribeiro |
| collection | DOAJ |
| description | Neuronal avalanches measured as consecutive bouts of thresholded field potentials represent a statistical signature that the brain operates near a critical point. In theory, criticality optimizes stimulus sensitivity, information transmission, computational capability and mnemonic repertoires size. Field potential avalanches recorded via multielectrode arrays from cortical slice cultures are repeatable spatiotemporal activity patterns. It remains unclear whether avalanches of action potentials observed in forebrain regions of freely-behaving rats also form recursive repertoires, and whether these have any behavioral relevance. Here we show that spike avalanches, recorded from hippocampus and sensory neocortex of freely-behaving rats, constitute distinct families of recursive spatiotemporal patterns. A significant number of those patterns were specific to a behavioral state. Although avalanches produced during sleep were mostly similar to others that occurred during waking, the repertoire of patterns recruited during sleep differed significantly from that of waking. More importantly, exposure to novel objects increased the rate at which new patterns arose, also leading to changes in post-exposure repertoires, which were significantly different from those before the exposure. A significant number of families occurred exclusively during periods of whisker contact with objects, but few were associated with specific objects. Altogether, the results provide original evidence linking behavior and criticality at the spike level: spike avalanches form repertoires that emerge in waking, recur during sleep, are diversified by novelty and contribute to object representation. |
| first_indexed | 2024-12-14T21:37:48Z |
| format | Article |
| id | doaj.art-cf6175783ce345fc8d712d9c7ec94046 |
| institution | Directory Open Access Journal |
| issn | 1662-5110 |
| language | English |
| last_indexed | 2024-12-14T21:37:48Z |
| publishDate | 2016-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neural Circuits |
| spelling | doaj.art-cf6175783ce345fc8d712d9c7ec940462022-12-21T22:46:32ZengFrontiers Media S.A.Frontiers in Neural Circuits1662-51102016-03-011010.3389/fncir.2016.00016176210Repertoires of spike avalanches are modulated by behavior and noveltyTiago Lins Ribeiro0Tiago Lins Ribeiro1Sidarta eRibeiro2Mauro eCopelli3National Institutes of HealthFederal University of PernambucoFederal University of Rio Grande do NorteFederal University of PernambucoNeuronal avalanches measured as consecutive bouts of thresholded field potentials represent a statistical signature that the brain operates near a critical point. In theory, criticality optimizes stimulus sensitivity, information transmission, computational capability and mnemonic repertoires size. Field potential avalanches recorded via multielectrode arrays from cortical slice cultures are repeatable spatiotemporal activity patterns. It remains unclear whether avalanches of action potentials observed in forebrain regions of freely-behaving rats also form recursive repertoires, and whether these have any behavioral relevance. Here we show that spike avalanches, recorded from hippocampus and sensory neocortex of freely-behaving rats, constitute distinct families of recursive spatiotemporal patterns. A significant number of those patterns were specific to a behavioral state. Although avalanches produced during sleep were mostly similar to others that occurred during waking, the repertoire of patterns recruited during sleep differed significantly from that of waking. More importantly, exposure to novel objects increased the rate at which new patterns arose, also leading to changes in post-exposure repertoires, which were significantly different from those before the exposure. A significant number of families occurred exclusively during periods of whisker contact with objects, but few were associated with specific objects. Altogether, the results provide original evidence linking behavior and criticality at the spike level: spike avalanches form repertoires that emerge in waking, recur during sleep, are diversified by novelty and contribute to object representation.http://journal.frontiersin.org/Journal/10.3389/fncir.2016.00016/fullAvalanchesMemorySleepCriticalitypatternsspikes |
| spellingShingle | Tiago Lins Ribeiro Tiago Lins Ribeiro Sidarta eRibeiro Mauro eCopelli Repertoires of spike avalanches are modulated by behavior and novelty Frontiers in Neural Circuits Avalanches Memory Sleep Criticality patterns spikes |
| title | Repertoires of spike avalanches are modulated by behavior and novelty |
| title_full | Repertoires of spike avalanches are modulated by behavior and novelty |
| title_fullStr | Repertoires of spike avalanches are modulated by behavior and novelty |
| title_full_unstemmed | Repertoires of spike avalanches are modulated by behavior and novelty |
| title_short | Repertoires of spike avalanches are modulated by behavior and novelty |
| title_sort | repertoires of spike avalanches are modulated by behavior and novelty |
| topic | Avalanches Memory Sleep Criticality patterns spikes |
| url | http://journal.frontiersin.org/Journal/10.3389/fncir.2016.00016/full |
| work_keys_str_mv | AT tiagolinsribeiro repertoiresofspikeavalanchesaremodulatedbybehaviorandnovelty AT tiagolinsribeiro repertoiresofspikeavalanchesaremodulatedbybehaviorandnovelty AT sidartaeribeiro repertoiresofspikeavalanchesaremodulatedbybehaviorandnovelty AT mauroecopelli repertoiresofspikeavalanchesaremodulatedbybehaviorandnovelty |