Traveling across Life Sciences with Acetophenone—A Simple Ketone That Has Special Multipurpose Missions
Each metabolite, regardless of its molecular simplicity or complexity, has a mission or function in the organism biosynthesizing it. In this review, the biological, allelochemical, and chemical properties of acetophenone, as a metabolite involved in multiple interactions with various (mi-cro)organis...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/1/370 |
| _version_ | 1797431448674762752 |
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| author | Fedor I. Zubkov Vladimir V. Kouznetsov |
| author_facet | Fedor I. Zubkov Vladimir V. Kouznetsov |
| author_sort | Fedor I. Zubkov |
| collection | DOAJ |
| description | Each metabolite, regardless of its molecular simplicity or complexity, has a mission or function in the organism biosynthesizing it. In this review, the biological, allelochemical, and chemical properties of acetophenone, as a metabolite involved in multiple interactions with various (mi-cro)organisms, are discussed. Further, the details of its biogenesis and chemical synthesis are provided, and the possibility of its application in different areas of life sciences, i.e., the status quo of acetophenone and its simple substituted analogs, is examined. In particular, natural and synthetic simple acetophenone derivatives are analyzed as promising agrochemicals and useful scaffolds for drug research and development. |
| first_indexed | 2024-03-09T09:44:05Z |
| format | Article |
| id | doaj.art-cf6421fa202542638c44dff46193c1c9 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T09:44:05Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-cf6421fa202542638c44dff46193c1c92023-12-02T00:42:41ZengMDPI AGMolecules1420-30492023-01-0128137010.3390/molecules28010370Traveling across Life Sciences with Acetophenone—A Simple Ketone That Has Special Multipurpose MissionsFedor I. Zubkov0Vladimir V. Kouznetsov1Department of Organic Chemistry, Рeoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, 117198 Moscow, RussiaLaboratorio de Química Orgánica y Biomolecular, Escuela de Química, Universidad Industrial de Santander, Cl. 9 # Cra 27, A.A., Bucaramanga 680006, ColombiaEach metabolite, regardless of its molecular simplicity or complexity, has a mission or function in the organism biosynthesizing it. In this review, the biological, allelochemical, and chemical properties of acetophenone, as a metabolite involved in multiple interactions with various (mi-cro)organisms, are discussed. Further, the details of its biogenesis and chemical synthesis are provided, and the possibility of its application in different areas of life sciences, i.e., the status quo of acetophenone and its simple substituted analogs, is examined. In particular, natural and synthetic simple acetophenone derivatives are analyzed as promising agrochemicals and useful scaffolds for drug research and development.https://www.mdpi.com/1420-3049/28/1/370acetophenonessecondary metabolitesbiological propertiesallelochemical interactionstoxicity |
| spellingShingle | Fedor I. Zubkov Vladimir V. Kouznetsov Traveling across Life Sciences with Acetophenone—A Simple Ketone That Has Special Multipurpose Missions Molecules acetophenones secondary metabolites biological properties allelochemical interactions toxicity |
| title | Traveling across Life Sciences with Acetophenone—A Simple Ketone That Has Special Multipurpose Missions |
| title_full | Traveling across Life Sciences with Acetophenone—A Simple Ketone That Has Special Multipurpose Missions |
| title_fullStr | Traveling across Life Sciences with Acetophenone—A Simple Ketone That Has Special Multipurpose Missions |
| title_full_unstemmed | Traveling across Life Sciences with Acetophenone—A Simple Ketone That Has Special Multipurpose Missions |
| title_short | Traveling across Life Sciences with Acetophenone—A Simple Ketone That Has Special Multipurpose Missions |
| title_sort | traveling across life sciences with acetophenone a simple ketone that has special multipurpose missions |
| topic | acetophenones secondary metabolites biological properties allelochemical interactions toxicity |
| url | https://www.mdpi.com/1420-3049/28/1/370 |
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