Comprehensive single-cell analysis reveals novel anergic antigen-presenting cell subtypes in human sepsis

Comprehensive single-cell analysis reveals novel anergic antigen-presenting cell subtypes in human sepsis

BackgroundSepsis is a life-threatening condition with high mortality. A few studies have emerged utilizing single-cell RNA sequencing (scRNA-seq) to analyze gene expression at the single-cell resolution in sepsis, but a comprehensive high-resolution analysis of blood antigen-presenting cells has not...

Full description

Bibliographic Details
Main Authors: Tuo Zhang, Guodong Lian, Wei Fang, Lei Tian, Wenhao Ma, Jicheng Zhang, Zhaoli Meng, Hongna Yang, Chunting Wang, Chengguo Wei, Man Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
sepsis
antigen-presenting cells
dendritic cells
immunosuppression
monocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1257572/full

Similar Items

Similar Items