Tuberculosis Disparity between US-born Blacks and Whites, Houston, Texas, USA

Tuberculosis (TB) rates in the United States are disproportionately high for certain ethnic minorities. Using univariate and multivariate analyses, we compared data for 1,318 US-born blacks with 565 US-born non-Hispanic whites who participated in the Houston TB Initiative (1995–2004). All available...

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Main Authors: Jose A. Serpa, Larry D. Teeter, James M. Musser, Edward A. Graviss
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2009-06-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/15/6/08-1617_article
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author Jose A. Serpa
Larry D. Teeter
James M. Musser
Edward A. Graviss
author_facet Jose A. Serpa
Larry D. Teeter
James M. Musser
Edward A. Graviss
author_sort Jose A. Serpa
collection DOAJ
description Tuberculosis (TB) rates in the United States are disproportionately high for certain ethnic minorities. Using univariate and multivariate analyses, we compared data for 1,318 US-born blacks with 565 US-born non-Hispanic whites who participated in the Houston TB Initiative (1995–2004). All available Mycobacterium tuberculosis isolates underwent susceptibility and genotype testing (insertion sequence 6110 restriction fragment length polymorphism, spoligotyping, and genetic grouping). TB in blacks was associated with younger age, inner city residence, HIV seropositivity, and drug resistance. TB cases clustered in 82% and 77% of blacks and whites, respectively (p = 0.46). Three clusters had >100 patients each, including 1 cluster with a predominance of blacks. Size of TB clusters was unexpectedly large, underscoring the ongoing transmission of TB in Houston, particularly among blacks.
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spelling doaj.art-cf65d34731994cf4b8691427737be5572022-12-21T22:49:33ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592009-06-0115689990410.3201/eid1506.081617Tuberculosis Disparity between US-born Blacks and Whites, Houston, Texas, USAJose A. SerpaLarry D. TeeterJames M. MusserEdward A. GravissTuberculosis (TB) rates in the United States are disproportionately high for certain ethnic minorities. Using univariate and multivariate analyses, we compared data for 1,318 US-born blacks with 565 US-born non-Hispanic whites who participated in the Houston TB Initiative (1995–2004). All available Mycobacterium tuberculosis isolates underwent susceptibility and genotype testing (insertion sequence 6110 restriction fragment length polymorphism, spoligotyping, and genetic grouping). TB in blacks was associated with younger age, inner city residence, HIV seropositivity, and drug resistance. TB cases clustered in 82% and 77% of blacks and whites, respectively (p = 0.46). Three clusters had >100 patients each, including 1 cluster with a predominance of blacks. Size of TB clusters was unexpectedly large, underscoring the ongoing transmission of TB in Houston, particularly among blacks.https://wwwnc.cdc.gov/eid/article/15/6/08-1617_articleMycobacterium tuberculosistuberculosis and other mycobacteriaepidemiologybacteriaminoritiesTexas
spellingShingle Jose A. Serpa
Larry D. Teeter
James M. Musser
Edward A. Graviss
Tuberculosis Disparity between US-born Blacks and Whites, Houston, Texas, USA
Emerging Infectious Diseases
Mycobacterium tuberculosis
tuberculosis and other mycobacteria
epidemiology
bacteria
minorities
Texas
title Tuberculosis Disparity between US-born Blacks and Whites, Houston, Texas, USA
title_full Tuberculosis Disparity between US-born Blacks and Whites, Houston, Texas, USA
title_fullStr Tuberculosis Disparity between US-born Blacks and Whites, Houston, Texas, USA
title_full_unstemmed Tuberculosis Disparity between US-born Blacks and Whites, Houston, Texas, USA
title_short Tuberculosis Disparity between US-born Blacks and Whites, Houston, Texas, USA
title_sort tuberculosis disparity between us born blacks and whites houston texas usa
topic Mycobacterium tuberculosis
tuberculosis and other mycobacteria
epidemiology
bacteria
minorities
Texas
url https://wwwnc.cdc.gov/eid/article/15/6/08-1617_article
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