Periductal bile acid exposure causes cholangiocyte injury and fibrosis.

<h4>Introduction</h4>Bile duct integrity is essential for the maintenance of the structure and function of the biliary tree. We previously showed that cholangiocyte injury in a toxic model of biliary atresia leads to increased monolayer permeability. Increased epithelial permeability was...

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Bibliographic Details
Main Authors: Miri Dotan, Sophia Fried, Adi Har-Zahav, Raanan Shamir, Rebecca G Wells, Orith Waisbourd-Zinman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0265418