Seroprevalence of Chikungunya virus infection in a Tertiary Care Hospital, Warangal, Telangana, South India
Introduction: The Chikungunya virus, an Alpha virus belongs to the Togaviridae family which infects via the vector Aedes spp. mosquitoes, is the cause of the Chikungunya sickness. The most prevalent symptoms are an abruptly rising temperature, rash, and acute arthralgia. Similar to other arbovir...
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| Format: | Article |
| Language: | English |
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Universitas Brawijaya
2023-11-01
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| Series: | Clinical and Research Journal in Internal Medicine |
| Subjects: | |
| Online Access: | https://crjim.ub.ac.id/index.php/crjim/article/view/164 |
| _version_ | 1797405595654946816 |
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| author | Gudikandula Krishna S Sreedevi Abdul Khan |
| author_facet | Gudikandula Krishna S Sreedevi Abdul Khan |
| author_sort | Gudikandula Krishna |
| collection | DOAJ |
| description | Introduction:
The Chikungunya virus, an Alpha virus belongs to the Togaviridae family which infects via the vector Aedes spp. mosquitoes, is the cause of the Chikungunya sickness. The most prevalent symptoms are an abruptly rising temperature, rash, and acute arthralgia. Similar to other arboviral diseases such as Dengue and Japanese B encephalitis infections, it is a serious public health issue.
Methods: A total of 3027 blood samples were received from suspected cases of Chikungunya in the Tertiary Care Hospital, Warangal, Telangana. Over a period of 17 months, this study was conducted. Nearly 5-10ml of blood was collected from the patients after 5 days of fever, and the serum was separated. Using an IgM antibody capture ELISA kit manufactured by NIV (NIV, Pune, India).
Results: In our study population of 3027 during 12 months, 313 Chikungunya cases (10.34%) were found to be seropositive for Chikungunya by IgM ELISA. Most cases were from 0-10 Years (24.60%), followed by 11-20 years (17.25%). Regarding the sex ratio of the total affected cases, 53.35% were males, and 46.64% were females. A maximum number of positives were seen in September, November, and October, which were found to be 35.46%, 18.84%, and 17.57%.
Conclusion: The study found a seroprevalence rate of 23.06% for Chikungunya, with a notable increase in frequency during the monsoon season. Additionally, the virus was found to disproportionately affect individuals in the productive age range of the population. |
| first_indexed | 2024-03-09T03:12:16Z |
| format | Article |
| id | doaj.art-cf66153f626a44c0b287be4c40f7decf |
| institution | Directory Open Access Journal |
| issn | 2723-5130 2723-5122 |
| language | English |
| last_indexed | 2024-03-09T03:12:16Z |
| publishDate | 2023-11-01 |
| publisher | Universitas Brawijaya |
| record_format | Article |
| series | Clinical and Research Journal in Internal Medicine |
| spelling | doaj.art-cf66153f626a44c0b287be4c40f7decf2023-12-04T02:33:24ZengUniversitas BrawijayaClinical and Research Journal in Internal Medicine2723-51302723-51222023-11-014246446910.21776/ub.crjim.2023.004.02.05114Seroprevalence of Chikungunya virus infection in a Tertiary Care Hospital, Warangal, Telangana, South IndiaGudikandula Krishna0S Sreedevi1Abdul Khan2Virus Research and Diagnostic Laboratory, Kakatiya Medical College, Warangal, Telangana, IndiaVirus Research and Diagnostic Laboratory, Kakatiya Medical College, Warangal, Telangana, IndiaVirus Research and Diagnostic Laboratory, Kakatiya Medical College, Warangal, Telangana, IndiaIntroduction: The Chikungunya virus, an Alpha virus belongs to the Togaviridae family which infects via the vector Aedes spp. mosquitoes, is the cause of the Chikungunya sickness. The most prevalent symptoms are an abruptly rising temperature, rash, and acute arthralgia. Similar to other arboviral diseases such as Dengue and Japanese B encephalitis infections, it is a serious public health issue. Methods: A total of 3027 blood samples were received from suspected cases of Chikungunya in the Tertiary Care Hospital, Warangal, Telangana. Over a period of 17 months, this study was conducted. Nearly 5-10ml of blood was collected from the patients after 5 days of fever, and the serum was separated. Using an IgM antibody capture ELISA kit manufactured by NIV (NIV, Pune, India). Results: In our study population of 3027 during 12 months, 313 Chikungunya cases (10.34%) were found to be seropositive for Chikungunya by IgM ELISA. Most cases were from 0-10 Years (24.60%), followed by 11-20 years (17.25%). Regarding the sex ratio of the total affected cases, 53.35% were males, and 46.64% were females. A maximum number of positives were seen in September, November, and October, which were found to be 35.46%, 18.84%, and 17.57%. Conclusion: The study found a seroprevalence rate of 23.06% for Chikungunya, with a notable increase in frequency during the monsoon season. Additionally, the virus was found to disproportionately affect individuals in the productive age range of the population.https://crjim.ub.ac.id/index.php/crjim/article/view/164seroprevalancevirus |
| spellingShingle | Gudikandula Krishna S Sreedevi Abdul Khan Seroprevalence of Chikungunya virus infection in a Tertiary Care Hospital, Warangal, Telangana, South India Clinical and Research Journal in Internal Medicine seroprevalance virus |
| title | Seroprevalence of Chikungunya virus infection in a Tertiary Care Hospital, Warangal, Telangana, South India |
| title_full | Seroprevalence of Chikungunya virus infection in a Tertiary Care Hospital, Warangal, Telangana, South India |
| title_fullStr | Seroprevalence of Chikungunya virus infection in a Tertiary Care Hospital, Warangal, Telangana, South India |
| title_full_unstemmed | Seroprevalence of Chikungunya virus infection in a Tertiary Care Hospital, Warangal, Telangana, South India |
| title_short | Seroprevalence of Chikungunya virus infection in a Tertiary Care Hospital, Warangal, Telangana, South India |
| title_sort | seroprevalence of chikungunya virus infection in a tertiary care hospital warangal telangana south india |
| topic | seroprevalance virus |
| url | https://crjim.ub.ac.id/index.php/crjim/article/view/164 |
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