Secreted expression of an active human interferon‐beta (HuIFNβ) in Kluyveromyces lactis

Interferon‐beta (IFNβ) is a cytokine involved in the antiviral, anti‐proliferative and immunomodulatory responses of cells, and a potent drug for multiple sclerosis. Human interferon beta (HuIFNβ) gene fused with the glucoamylase signal sequence in the N‐terminus and 6 His Tag in the C‐terminus was...

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Bibliographic Details
Main Authors: Aravind Madhavan, Rajeev Kumar Sukumaran
Format: Article
Language:English
Published: Wiley-VCH 2016-05-01
Series:Engineering in Life Sciences
Subjects:
Online Access:https://doi.org/10.1002/elsc.201500120