Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services
With the rapid evolving of emerging pathogens and residual risk of bacterial contamination in platelets, they continue to pose a constant threat to the safety of blood supply despite effort implemented to mitigate such risk via conventional measures and testing. Three photochemical based advanced pa...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | Journal of Photochemistry and Photobiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666469021000646 |
| _version_ | 1818461421542834176 |
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| author | Hong Liu Xun Wang |
| author_facet | Hong Liu Xun Wang |
| author_sort | Hong Liu |
| collection | DOAJ |
| description | With the rapid evolving of emerging pathogens and residual risk of bacterial contamination in platelets, they continue to pose a constant threat to the safety of blood supply despite effort implemented to mitigate such risk via conventional measures and testing. Three photochemical based advanced pathogen reduction technology (PRT) that utilize amotosalen, riboflavin and UVC only offer some of the unique advantages over conventional approaches. They have demonstrated superior pathogen reduction capability against various emerging viruses, bacteria, parasites and leukocytes, as well as acceptable safety and clinical efficacy based on reports, studies and clinical trials. Although concern related to cost and adverse transfusion reaction of PRT application remains, with further study and continue improvement, future PRT will continue to play a paramount role in assuring the safety of blood and blood products. |
| first_indexed | 2024-12-14T23:45:53Z |
| format | Article |
| id | doaj.art-cf66cc645a144aa9818b66c221012edb |
| institution | Directory Open Access Journal |
| issn | 2666-4690 |
| language | English |
| last_indexed | 2024-12-14T23:45:53Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Photochemistry and Photobiology |
| spelling | doaj.art-cf66cc645a144aa9818b66c221012edb2022-12-21T22:43:23ZengElsevierJournal of Photochemistry and Photobiology2666-46902021-12-018100079Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion servicesHong Liu0Xun Wang1Department of Transfusion-transmitted infectious Disease, Institute of Blood Transfusion, Shanghai Blood Center, 1191 Hong Qiao Rd, Shanghai, ChinaDepartment of Transfusion-transmitted infectious Disease, Institute of Blood Transfusion, Shanghai Blood Center, 1191 Hong Qiao Rd, Shanghai, China; Corresponding author.With the rapid evolving of emerging pathogens and residual risk of bacterial contamination in platelets, they continue to pose a constant threat to the safety of blood supply despite effort implemented to mitigate such risk via conventional measures and testing. Three photochemical based advanced pathogen reduction technology (PRT) that utilize amotosalen, riboflavin and UVC only offer some of the unique advantages over conventional approaches. They have demonstrated superior pathogen reduction capability against various emerging viruses, bacteria, parasites and leukocytes, as well as acceptable safety and clinical efficacy based on reports, studies and clinical trials. Although concern related to cost and adverse transfusion reaction of PRT application remains, with further study and continue improvement, future PRT will continue to play a paramount role in assuring the safety of blood and blood products.http://www.sciencedirect.com/science/article/pii/S2666469021000646Pathogen reduction technologyPR systemPathogen reductionEmerging infectious diseaseTransfusion-transmitted infection, Blood safetyVirus |
| spellingShingle | Hong Liu Xun Wang Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services Journal of Photochemistry and Photobiology Pathogen reduction technology PR system Pathogen reduction Emerging infectious disease Transfusion-transmitted infection, Blood safety Virus |
| title | Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services |
| title_full | Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services |
| title_fullStr | Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services |
| title_full_unstemmed | Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services |
| title_short | Pathogen reduction technology for blood component: A promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services |
| title_sort | pathogen reduction technology for blood component a promising solution for prevention of emerging infectious disease and bacterial contamination in blood transfusion services |
| topic | Pathogen reduction technology PR system Pathogen reduction Emerging infectious disease Transfusion-transmitted infection, Blood safety Virus |
| url | http://www.sciencedirect.com/science/article/pii/S2666469021000646 |
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