The combination of DNA methylome and transcriptome revealed the intergenerational inheritance on the influence of advanced maternal age

Abstract Background The number of women delivering at advanced maternal age (AMA; > = 35) continuously increases in developed and high‐income countries. Large cohort studies have associated AMA with increased risks of various pregnancy complications and adverse pregnancy outcomes, which raises gr...

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Bibliographic Details
Main Authors: Lingyue Hua, Wei Chen, Yan Meng, Meng Qin, Zhiqiang Yan, Rui Yang, Qiang Liu, Yuan Wei, Yangyu Zhao, Liying Yan, Jie Qiao
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.990