Desmoplastic fibroma of bone: A rare bone tumour
We identified thirteen patients with desmoplastic fibroma of bone treated at our institute over a 30 year period. The patients had a mean age of 25.9 years; eight were female. The incidence of desmoplastic fibroma of bone in all patients with benign bone tumours in our population is 0.003%. Surgical...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2014-11-01
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| Series: | Journal of Bone Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212137414200042 |
| _version_ | 1818584962697265152 |
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| author | S. Evans A. Ramasamy L. Jeys R. Grimer |
| author_facet | S. Evans A. Ramasamy L. Jeys R. Grimer |
| author_sort | S. Evans |
| collection | DOAJ |
| description | We identified thirteen patients with desmoplastic fibroma of bone treated at our institute over a 30 year period. The patients had a mean age of 25.9 years; eight were female. The incidence of desmoplastic fibroma of bone in all patients with benign bone tumours in our population is 0.003%. Surgical treatment ranged from primary amputation to intra-lesional curettage. The incidence of local recurrence was 15.4%. All cases of local recurrence after curettage or marginal excision demonstrated soft-tissue extension of their tumours on initial presentation suggesting that extra-osseous extension requires more radical surgery to control the disease.
This study presents the largest single centre series of desmoplastic fibroma of bone with a mean follow-up time of 8 years. We recommend wide surgical excision, particularly if the lesion can be resected without significant loss of function, as the treatment modality of choice with the lowest rate of recurrence. Patients undergoing intra-lesional or marginal resection need to be advised of the possibility of local recurrence and the need for long-term surveillance. |
| first_indexed | 2024-12-16T08:29:31Z |
| format | Article |
| id | doaj.art-cf73874358334c7c8ea5c49aad8b3569 |
| institution | Directory Open Access Journal |
| issn | 2212-1374 |
| language | English |
| last_indexed | 2024-12-16T08:29:31Z |
| publishDate | 2014-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Bone Oncology |
| spelling | doaj.art-cf73874358334c7c8ea5c49aad8b35692022-12-21T22:37:55ZengElsevierJournal of Bone Oncology2212-13742014-11-0133777910.1016/j.jbo.2014.08.001Desmoplastic fibroma of bone: A rare bone tumourS. EvansA. RamasamyL. JeysR. GrimerWe identified thirteen patients with desmoplastic fibroma of bone treated at our institute over a 30 year period. The patients had a mean age of 25.9 years; eight were female. The incidence of desmoplastic fibroma of bone in all patients with benign bone tumours in our population is 0.003%. Surgical treatment ranged from primary amputation to intra-lesional curettage. The incidence of local recurrence was 15.4%. All cases of local recurrence after curettage or marginal excision demonstrated soft-tissue extension of their tumours on initial presentation suggesting that extra-osseous extension requires more radical surgery to control the disease. This study presents the largest single centre series of desmoplastic fibroma of bone with a mean follow-up time of 8 years. We recommend wide surgical excision, particularly if the lesion can be resected without significant loss of function, as the treatment modality of choice with the lowest rate of recurrence. Patients undergoing intra-lesional or marginal resection need to be advised of the possibility of local recurrence and the need for long-term surveillance.http://www.sciencedirect.com/science/article/pii/S2212137414200042DesmoplasticFibromaBoneLocal recurrenceManagement |
| spellingShingle | S. Evans A. Ramasamy L. Jeys R. Grimer Desmoplastic fibroma of bone: A rare bone tumour Journal of Bone Oncology Desmoplastic Fibroma Bone Local recurrence Management |
| title | Desmoplastic fibroma of bone: A rare bone tumour |
| title_full | Desmoplastic fibroma of bone: A rare bone tumour |
| title_fullStr | Desmoplastic fibroma of bone: A rare bone tumour |
| title_full_unstemmed | Desmoplastic fibroma of bone: A rare bone tumour |
| title_short | Desmoplastic fibroma of bone: A rare bone tumour |
| title_sort | desmoplastic fibroma of bone a rare bone tumour |
| topic | Desmoplastic Fibroma Bone Local recurrence Management |
| url | http://www.sciencedirect.com/science/article/pii/S2212137414200042 |
| work_keys_str_mv | AT sevans desmoplasticfibromaofboneararebonetumour AT aramasamy desmoplasticfibromaofboneararebonetumour AT ljeys desmoplasticfibromaofboneararebonetumour AT rgrimer desmoplasticfibromaofboneararebonetumour |