LDLR promotes autophagy‐mediated cisplatin resistance in ovarian cancer associated with the PI3K/AKT/mTOR signaling pathway

LDLR promotes autophagy‐mediated cisplatin resistance in ovarian cancer associated with the PI3K/AKT/mTOR signaling pathway

Abstract Autophagy is one of the underlying causes of resistance to many antitumor drugs, including cisplatin (DDP). The low‐density lipoprotein receptor (LDLR) is a regulator of ovarian cancer (OC) progression. However, whether LDLR regulates DDP resistance in OC via autophagy‐related pathways rema...

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Bibliographic Details
Main Authors: Lei Liu, Yu‐Hui Sun, Ran An, Rong‐Jie Cheng, Nan Li, Jian‐Hua Zheng
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
autophagy
cisplatin resistance
low‐density lipoprotein receptor
ovarian cancer
Online Access:https://doi.org/10.1002/kjm2.12696

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