Thrombocytopenia and hyperthyroidism: A case report and literature review
Key Clinical Message Immune thrombocytopenic purpura (ITP) is very challenging to diagnose with concurrent comorbidities affecting platelet count including PAH and autoimmune thyroid disease. ITP resolution can be achieved with tailored treatment of the underlying conditions to avoid adverse events....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-10-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7960 |
| _version_ | 1797650438962544640 |
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| author | Pitchaporn Yingchoncharoen Mahmoud Abdelnabi Jerapas Thongpiya Alexandra Hoffman Hira Tariq Neha Mittal |
| author_facet | Pitchaporn Yingchoncharoen Mahmoud Abdelnabi Jerapas Thongpiya Alexandra Hoffman Hira Tariq Neha Mittal |
| author_sort | Pitchaporn Yingchoncharoen |
| collection | DOAJ |
| description | Key Clinical Message Immune thrombocytopenic purpura (ITP) is very challenging to diagnose with concurrent comorbidities affecting platelet count including PAH and autoimmune thyroid disease. ITP resolution can be achieved with tailored treatment of the underlying conditions to avoid adverse events. Abstract Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by a platelet count of <100 × 109/L in the absence of other causes of thrombocytopenia. It is classified as primary or idiopathic and secondary due to various coexisting conditions, including autoimmune thyroid diseases. It is especially challenging when the patient has comorbidities that affect platelet count easily, leading to anchoring bias. The first‐line treatment of ITP is corticosteroids, and it is also recommended to treat the primary causes of secondary ITP. Here, the authors report a case of secondary ITP in a patient with a recent diagnosis of Grave's disease and a history of idiopathic pulmonary hypertension with baseline chronic thrombocytopenia, possible mechanisms, and treatment strategies with a multidisciplinary approach. |
| first_indexed | 2024-03-11T16:00:23Z |
| format | Article |
| id | doaj.art-cf7e0466cc314acb869e19facebc67c4 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-11T16:00:23Z |
| publishDate | 2023-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-cf7e0466cc314acb869e19facebc67c42023-10-25T07:12:44ZengWileyClinical Case Reports2050-09042023-10-011110n/an/a10.1002/ccr3.7960Thrombocytopenia and hyperthyroidism: A case report and literature reviewPitchaporn Yingchoncharoen0Mahmoud Abdelnabi1Jerapas Thongpiya2Alexandra Hoffman3Hira Tariq4Neha Mittal5Department of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USADepartment of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USADepartment of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USADepartment of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USAShalamar Institute of Health Sciences Lahore PakistanDepartment of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USAKey Clinical Message Immune thrombocytopenic purpura (ITP) is very challenging to diagnose with concurrent comorbidities affecting platelet count including PAH and autoimmune thyroid disease. ITP resolution can be achieved with tailored treatment of the underlying conditions to avoid adverse events. Abstract Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by a platelet count of <100 × 109/L in the absence of other causes of thrombocytopenia. It is classified as primary or idiopathic and secondary due to various coexisting conditions, including autoimmune thyroid diseases. It is especially challenging when the patient has comorbidities that affect platelet count easily, leading to anchoring bias. The first‐line treatment of ITP is corticosteroids, and it is also recommended to treat the primary causes of secondary ITP. Here, the authors report a case of secondary ITP in a patient with a recent diagnosis of Grave's disease and a history of idiopathic pulmonary hypertension with baseline chronic thrombocytopenia, possible mechanisms, and treatment strategies with a multidisciplinary approach.https://doi.org/10.1002/ccr3.7960autoimmune diseaseGrave's diseaseimmune thrombocytopeniapulmonary arterial hypertensionthyroid disease |
| spellingShingle | Pitchaporn Yingchoncharoen Mahmoud Abdelnabi Jerapas Thongpiya Alexandra Hoffman Hira Tariq Neha Mittal Thrombocytopenia and hyperthyroidism: A case report and literature review Clinical Case Reports autoimmune disease Grave's disease immune thrombocytopenia pulmonary arterial hypertension thyroid disease |
| title | Thrombocytopenia and hyperthyroidism: A case report and literature review |
| title_full | Thrombocytopenia and hyperthyroidism: A case report and literature review |
| title_fullStr | Thrombocytopenia and hyperthyroidism: A case report and literature review |
| title_full_unstemmed | Thrombocytopenia and hyperthyroidism: A case report and literature review |
| title_short | Thrombocytopenia and hyperthyroidism: A case report and literature review |
| title_sort | thrombocytopenia and hyperthyroidism a case report and literature review |
| topic | autoimmune disease Grave's disease immune thrombocytopenia pulmonary arterial hypertension thyroid disease |
| url | https://doi.org/10.1002/ccr3.7960 |
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