Cardiac Rehabilitation and Endothelial Function
Endothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the m...
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Format: | Article |
Language: | English |
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MDPI AG
2020-08-01
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Series: | Journal of Clinical Medicine |
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Online Access: | https://www.mdpi.com/2077-0383/9/8/2487 |
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author | Gaetano Antonio Lanza Michele Golino Angelo Villano Oreste Lanza Priscilla Lamendola Augusto Fusco Massimo Leggio |
author_facet | Gaetano Antonio Lanza Michele Golino Angelo Villano Oreste Lanza Priscilla Lamendola Augusto Fusco Massimo Leggio |
author_sort | Gaetano Antonio Lanza |
collection | DOAJ |
description | Endothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the mechanisms of its beneficial effects remain only partially known. In this article, we review the studies that assessed the effect of CR on endothelial function in patients with various cardiac conditions. Available data show that CR significantly improves impaired endothelial function in these patients, which may contribute to the beneficial effects of CR on clinical outcome. |
first_indexed | 2024-03-10T18:01:33Z |
format | Article |
id | doaj.art-cf7f9d19aef54e59bc57b0ec9201bcc7 |
institution | Directory Open Access Journal |
issn | 2077-0383 |
language | English |
last_indexed | 2024-03-10T18:01:33Z |
publishDate | 2020-08-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Clinical Medicine |
spelling | doaj.art-cf7f9d19aef54e59bc57b0ec9201bcc72023-11-20T08:53:07ZengMDPI AGJournal of Clinical Medicine2077-03832020-08-0198248710.3390/jcm9082487Cardiac Rehabilitation and Endothelial FunctionGaetano Antonio Lanza0Michele Golino1Angelo Villano2Oreste Lanza3Priscilla Lamendola4Augusto Fusco5Massimo Leggio6Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDepartment of Heart and Vessels, Ospedale di Circolo, University of Insubria, 21100 Varese, ItalyFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDepartment of Clinical and Molecular Medicine and Psychology, Università La Sapienza, 00189 Roma, ItalyFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyFondazione Don Carlo Gnocchi IRCCS, 20147 Milan, ItalyCardiology Operative Unit, San Filippo Neri Hospital, 00135 Rome, ItalyEndothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the mechanisms of its beneficial effects remain only partially known. In this article, we review the studies that assessed the effect of CR on endothelial function in patients with various cardiac conditions. Available data show that CR significantly improves impaired endothelial function in these patients, which may contribute to the beneficial effects of CR on clinical outcome.https://www.mdpi.com/2077-0383/9/8/2487cardiac rehabilitationendothelial functionclinical outcome |
spellingShingle | Gaetano Antonio Lanza Michele Golino Angelo Villano Oreste Lanza Priscilla Lamendola Augusto Fusco Massimo Leggio Cardiac Rehabilitation and Endothelial Function Journal of Clinical Medicine cardiac rehabilitation endothelial function clinical outcome |
title | Cardiac Rehabilitation and Endothelial Function |
title_full | Cardiac Rehabilitation and Endothelial Function |
title_fullStr | Cardiac Rehabilitation and Endothelial Function |
title_full_unstemmed | Cardiac Rehabilitation and Endothelial Function |
title_short | Cardiac Rehabilitation and Endothelial Function |
title_sort | cardiac rehabilitation and endothelial function |
topic | cardiac rehabilitation endothelial function clinical outcome |
url | https://www.mdpi.com/2077-0383/9/8/2487 |
work_keys_str_mv | AT gaetanoantoniolanza cardiacrehabilitationandendothelialfunction AT michelegolino cardiacrehabilitationandendothelialfunction AT angelovillano cardiacrehabilitationandendothelialfunction AT orestelanza cardiacrehabilitationandendothelialfunction AT priscillalamendola cardiacrehabilitationandendothelialfunction AT augustofusco cardiacrehabilitationandendothelialfunction AT massimoleggio cardiacrehabilitationandendothelialfunction |