Cardiac Rehabilitation and Endothelial Function

Endothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the m...

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Main Authors: Gaetano Antonio Lanza, Michele Golino, Angelo Villano, Oreste Lanza, Priscilla Lamendola, Augusto Fusco, Massimo Leggio
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/9/8/2487
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author Gaetano Antonio Lanza
Michele Golino
Angelo Villano
Oreste Lanza
Priscilla Lamendola
Augusto Fusco
Massimo Leggio
author_facet Gaetano Antonio Lanza
Michele Golino
Angelo Villano
Oreste Lanza
Priscilla Lamendola
Augusto Fusco
Massimo Leggio
author_sort Gaetano Antonio Lanza
collection DOAJ
description Endothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the mechanisms of its beneficial effects remain only partially known. In this article, we review the studies that assessed the effect of CR on endothelial function in patients with various cardiac conditions. Available data show that CR significantly improves impaired endothelial function in these patients, which may contribute to the beneficial effects of CR on clinical outcome.
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spelling doaj.art-cf7f9d19aef54e59bc57b0ec9201bcc72023-11-20T08:53:07ZengMDPI AGJournal of Clinical Medicine2077-03832020-08-0198248710.3390/jcm9082487Cardiac Rehabilitation and Endothelial FunctionGaetano Antonio Lanza0Michele Golino1Angelo Villano2Oreste Lanza3Priscilla Lamendola4Augusto Fusco5Massimo Leggio6Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDepartment of Heart and Vessels, Ospedale di Circolo, University of Insubria, 21100 Varese, ItalyFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDepartment of Clinical and Molecular Medicine and Psychology, Università La Sapienza, 00189 Roma, ItalyFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyFondazione Don Carlo Gnocchi IRCCS, 20147 Milan, ItalyCardiology Operative Unit, San Filippo Neri Hospital, 00135 Rome, ItalyEndothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the mechanisms of its beneficial effects remain only partially known. In this article, we review the studies that assessed the effect of CR on endothelial function in patients with various cardiac conditions. Available data show that CR significantly improves impaired endothelial function in these patients, which may contribute to the beneficial effects of CR on clinical outcome.https://www.mdpi.com/2077-0383/9/8/2487cardiac rehabilitationendothelial functionclinical outcome
spellingShingle Gaetano Antonio Lanza
Michele Golino
Angelo Villano
Oreste Lanza
Priscilla Lamendola
Augusto Fusco
Massimo Leggio
Cardiac Rehabilitation and Endothelial Function
Journal of Clinical Medicine
cardiac rehabilitation
endothelial function
clinical outcome
title Cardiac Rehabilitation and Endothelial Function
title_full Cardiac Rehabilitation and Endothelial Function
title_fullStr Cardiac Rehabilitation and Endothelial Function
title_full_unstemmed Cardiac Rehabilitation and Endothelial Function
title_short Cardiac Rehabilitation and Endothelial Function
title_sort cardiac rehabilitation and endothelial function
topic cardiac rehabilitation
endothelial function
clinical outcome
url https://www.mdpi.com/2077-0383/9/8/2487
work_keys_str_mv AT gaetanoantoniolanza cardiacrehabilitationandendothelialfunction
AT michelegolino cardiacrehabilitationandendothelialfunction
AT angelovillano cardiacrehabilitationandendothelialfunction
AT orestelanza cardiacrehabilitationandendothelialfunction
AT priscillalamendola cardiacrehabilitationandendothelialfunction
AT augustofusco cardiacrehabilitationandendothelialfunction
AT massimoleggio cardiacrehabilitationandendothelialfunction