PRMT5 regulates the polysaccharide content by controlling the splicing of thaumatin-like protein in Ganoderma lucidum

PRMT5 regulates the polysaccharide content by controlling the splicing of thaumatin-like protein in Ganoderma lucidum

ABSTRACT In the current study, the silencing of protein arginine methyltransferase 5 (PRMT5) decreased the polysaccharide content of Ganoderma lucidum compared to that of the wild-type (WT) strain. Furthermore, RNA-seq screening showed that the glycan degradation process-related gene thaumatin-like...

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Bibliographic Details
Main Authors: Rui Liu, Zhengyan Yang, Tao Yang, Zi Wang, Xin Chen, Jing Zhu, Ang Ren, Liang Shi, Hanshou Yu, Mingwen Zhao
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
PRMT5
alternative splicing
thaumatin-like protein
G. lucidum polysaccharide
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02906-23

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