Combining Human Genetics of Multiple Sclerosis with Oxidative Stress Phenotype for Drug Repositioning

In multiple sclerosis (MS), oxidative stress (OS) is implicated in the neurodegenerative processes that occur from the beginning of the disease. Unchecked OS initiates a vicious circle caused by its crosstalk with inflammation, leading to demyelination, axonal damage and neuronal loss. The failure o...

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Bibliographic Details
Main Authors: Stefania Olla, Maristella Steri, Alessia Formato, Michael B. Whalen, Silvia Corbisiero, Cristina Agresti
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/12/2064