Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming Roles
Antibiotic resistance has become increasingly prevalent in the environment. Many alternative strategies have been proposed for the treatment and prevention of diverse diseases in agriculture. Among them, the modulation of bacterial virulence to bypass antibiotic resistance or boost plant innate immu...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2022.885625/full |
| _version_ | 1818240230905348096 |
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| author | Ji Eun Kang Nayeon Yoo Byeong Jun Jeon Beom Seok Kim Beom Seok Kim Beom Seok Kim Eui-Hwan Chung Eui-Hwan Chung Eui-Hwan Chung |
| author_facet | Ji Eun Kang Nayeon Yoo Byeong Jun Jeon Beom Seok Kim Beom Seok Kim Beom Seok Kim Eui-Hwan Chung Eui-Hwan Chung Eui-Hwan Chung |
| author_sort | Ji Eun Kang |
| collection | DOAJ |
| description | Antibiotic resistance has become increasingly prevalent in the environment. Many alternative strategies have been proposed for the treatment and prevention of diverse diseases in agriculture. Among them, the modulation of bacterial virulence to bypass antibiotic resistance or boost plant innate immunity can be considered a promising drug target. Plant-produced natural products offer a broad spectrum of stereochemistry and a wide range of pharmacophores, providing a great diversity of biological activities. Here, we present a perspective on the putative role of plant-produced resveratrol oligomers as anti-virulence and plant-immune priming agents for efficient disease management. Resveratrol oligomers can decrease (1) bacterial motility directly and (2) indirectly by attenuating the bacterial type III secretion system (TT3S). They induce enhanced local immune responses mediated by two-layered plant innate immunity, demonstrating (3) a putative plant immune priming role. |
| first_indexed | 2024-12-12T13:10:09Z |
| format | Article |
| id | doaj.art-cf85ad31a10b45f781a1fcba7c0800c4 |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-12T13:10:09Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-cf85ad31a10b45f781a1fcba7c0800c42022-12-22T00:23:33ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2022-05-011310.3389/fpls.2022.885625885625Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming RolesJi Eun Kang0Nayeon Yoo1Byeong Jun Jeon2Beom Seok Kim3Beom Seok Kim4Beom Seok Kim5Eui-Hwan Chung6Eui-Hwan Chung7Eui-Hwan Chung8Institute of Life Science and Natural Resources, Korea University, Seoul, South KoreaDepartment of Plant Biotechnology, Graduate School, Korea University, Seoul, South KoreaSmart Farm Research Center, Korea Institute of Science and Technology, Gangneung Institute, Gangneung, South KoreaInstitute of Life Science and Natural Resources, Korea University, Seoul, South KoreaDepartment of Plant Biotechnology, Graduate School, Korea University, Seoul, South KoreaDivision of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, South KoreaInstitute of Life Science and Natural Resources, Korea University, Seoul, South KoreaDepartment of Plant Biotechnology, Graduate School, Korea University, Seoul, South KoreaDivision of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, South KoreaAntibiotic resistance has become increasingly prevalent in the environment. Many alternative strategies have been proposed for the treatment and prevention of diverse diseases in agriculture. Among them, the modulation of bacterial virulence to bypass antibiotic resistance or boost plant innate immunity can be considered a promising drug target. Plant-produced natural products offer a broad spectrum of stereochemistry and a wide range of pharmacophores, providing a great diversity of biological activities. Here, we present a perspective on the putative role of plant-produced resveratrol oligomers as anti-virulence and plant-immune priming agents for efficient disease management. Resveratrol oligomers can decrease (1) bacterial motility directly and (2) indirectly by attenuating the bacterial type III secretion system (TT3S). They induce enhanced local immune responses mediated by two-layered plant innate immunity, demonstrating (3) a putative plant immune priming role.https://www.frontiersin.org/articles/10.3389/fpls.2022.885625/fullanti-virulenceimmune-primingtype III secretion system (TT3S)resveratrol oligomersstilbene |
| spellingShingle | Ji Eun Kang Nayeon Yoo Byeong Jun Jeon Beom Seok Kim Beom Seok Kim Beom Seok Kim Eui-Hwan Chung Eui-Hwan Chung Eui-Hwan Chung Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming Roles Frontiers in Plant Science anti-virulence immune-priming type III secretion system (TT3S) resveratrol oligomers stilbene |
| title | Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming Roles |
| title_full | Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming Roles |
| title_fullStr | Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming Roles |
| title_full_unstemmed | Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming Roles |
| title_short | Resveratrol Oligomers, Plant-Produced Natural Products With Anti-virulence and Plant Immune-Priming Roles |
| title_sort | resveratrol oligomers plant produced natural products with anti virulence and plant immune priming roles |
| topic | anti-virulence immune-priming type III secretion system (TT3S) resveratrol oligomers stilbene |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2022.885625/full |
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