<i>MTHFR</i> and <i>VDR</i> Polymorphisms Improve the Prognostic Value of <i>MYCN</i> Status on Overall Survival in Neuroblastoma Patients

<i>MTHFR</i> and <i>VDR</i> Polymorphisms Improve the Prognostic Value of <i>MYCN</i> Status on Overall Survival in Neuroblastoma Patients

Single nucleotide polymorphisms (SNPs) in Pharmacogenetics can play an important role in the outcomes of the chemotherapy treatment in Neuroblastoma, helping doctors maximize efficacy and minimize toxicity. Employing AgenaBioscience MassArray, 96 SNPs were genotyped in 95 patients looking for associ...

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Bibliographic Details
Main Authors: Gladys G. Olivera, Yania Yáñez, Pablo Gargallo, Luis Sendra, Salvador F. Aliño, Vanessa Segura, Miguel Ángel Sanz, Adela Cañete, Victoria Castel, Jaime Font De Mora, David Hervás, Pablo Berlanga, María José Herrero
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
pharmacogenetics
neuroblastoma
survival
toxicity
SNP
Online Access:https://www.mdpi.com/1422-0067/21/8/2714

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