Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair

Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair

Structural cardiac remodeling after ischemic injury can induce a transition to heart failure from progressive loss of cardiac function. Cellular regenerative therapies are promising but face significant translational hurdles. Tissue extracellular matrix (ECM) holds the necessary environmental cues t...

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Bibliographic Details
Main Authors: Holly E.M. Mewhort, MD, PhD, Daniyil A. Svystonyuk, BSc, Jeannine D. Turnbull, BSc, Guoqi Teng, PhD, Darrell D. Belke, PhD, David G. Guzzardi, BSc, Daniel S. Park, BSc, Sean Kang, BSc, Morley D. Hollenberg, MD, PhD, Paul W.M. Fedak, MD, PhD
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:JACC: Basic to Translational Science
Subjects:
extracellular matrix
regeneration
vasculogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X17301389

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