A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma

A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma

Abstract Background Genetic variants associated with acute side effects of radiotherapy in nasopharyngeal carcinoma (NPC) remain largely unknown. Methods We performed a two-stage genome-wide association analysis including a total of 1084 patients, where 319 individuals in the discovery stage were ge...

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Bibliographic Details
Main Authors: Yang Wang, Fan Xiao, Yi Zhao, Chen-Xue Mao, Lu-Lu Yu, Lei-Yun Wang, Qi Xiao, Rong Liu, Xi Li, Howard L. McLeod, Bi-Wen Hu, Yu-Ling Huang, Qiao-Li Lv, Xiao-Xue Xie, Wei-Hua Huang, Wei Zhang, Cheng-Xian Guo, Jin-Gao Li, Ji-Ye Yin
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Molecular Cancer
Subjects:
Nasopharyngeal carcinoma
GWAS
Radiogenomics
Radiotherapy toxicity
Skin reaction
Dysphagia
Online Access:https://doi.org/10.1186/s12943-022-01631-8

Internet

https://doi.org/10.1186/s12943-022-01631-8

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