Clearance of persistent SARS-CoV-2 associates with increased neutralizing antibodies in advanced HIV disease post-ART initiation

Clearance of persistent SARS-CoV-2 associates with increased neutralizing antibodies in advanced HIV disease post-ART initiation

Abstract SARS-CoV-2 clearance requires adaptive immunity but the contribution of neutralizing antibodies and T cells in different immune states is unclear. Here we ask which adaptive immune responses associate with clearance of long-term SARS-CoV-2 infection in HIV-mediated immunosuppression after s...

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Main Authors: Farina Karim, Catherine Riou, Mallory Bernstein, Zesuliwe Jule, Gila Lustig, Strauss van Graan, Roanne S. Keeton, Janine-Lee Upton, Yashica Ganga, Khadija Khan, Kajal Reedoy, Matilda Mazibuko, Katya Govender, Kershnee Thambu, Nokuthula Ngcobo, Elizabeth Venter, Zanele Makhado, Willem Hanekom, Anne von Gottberg, Monjurul Hoque, Quarraisha Abdool Karim, Salim S. Abdool Karim, Nithendra Manickchund, Nombulelo Magula, Bernadett I. Gosnell, Richard J. Lessells, Penny L. Moore, Wendy A. Burgers, Tulio de Oliveira, Mahomed-Yunus S. Moosa, Alex Sigal
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46673-2

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