Methicillin-resistant Staphylococcus aureus appendicitis
Methicillin-resistant Staphylococcus aureus (MRSA) is commonly isolated from complex intra-abdominal infections. There have been reports of MRSA isolates from various abdominal infections such as diverticulitis, spontaneous bacterial peritonitis and infected peritoneal dialysis catheters. However, t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-05-01
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| Series: | Journal of Pediatric Surgery Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213576617303391 |
| _version_ | 1818246108757884928 |
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| author | Aditya Safaya Morgan Stockberger Karl I. Li Guiqing Wang Seunghwan Pee Gustavo Stringel |
| author_facet | Aditya Safaya Morgan Stockberger Karl I. Li Guiqing Wang Seunghwan Pee Gustavo Stringel |
| author_sort | Aditya Safaya |
| collection | DOAJ |
| description | Methicillin-resistant Staphylococcus aureus (MRSA) is commonly isolated from complex intra-abdominal infections. There have been reports of MRSA isolates from various abdominal infections such as diverticulitis, spontaneous bacterial peritonitis and infected peritoneal dialysis catheters. However, there has been no report of MRSA infection related to appendicitis.We present the first case series of MRSA isolated from the abdominal fluid of two patients presenting with appendicitis and managed with laparoscopic appendectomy. Both patients were found to have MRSA isolates from the peritoneal fluid culture.The two patients underwent successful laparoscopic appendectomy and were discharged on appropriate antibiotic coverage for MRSA to complete the course of treatment.Multiple strategies have been involved to manage MRSA infection. Appropriate targeted therapy with source control remains the mainstay of intra-abdominal infections. We present two cases with MRSA isolates from the peritoneal fluid of patients with acute appendicitis. This finding highlights the importance of obtaining intra-operative cultures during appendectomies to guide post-operative antibiotic therapy. Appropriate antimicrobial therapy is the mainstay of treating these infections and preventing the emergence of multi-drug resistant organisms. Keywords: MRSA, MRSA appendicitis, Intra-operative peritoneal cultures |
| first_indexed | 2024-12-12T14:43:34Z |
| format | Article |
| id | doaj.art-cf997522a8ef4b03884ba2935e38d5bf |
| institution | Directory Open Access Journal |
| issn | 2213-5766 |
| language | English |
| last_indexed | 2024-12-12T14:43:34Z |
| publishDate | 2018-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pediatric Surgery Case Reports |
| spelling | doaj.art-cf997522a8ef4b03884ba2935e38d5bf2022-12-22T00:21:10ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662018-05-01324345Methicillin-resistant Staphylococcus aureus appendicitisAditya Safaya0Morgan Stockberger1Karl I. Li2Guiqing Wang3Seunghwan Pee4Gustavo Stringel5Division of Pediatric Surgery, New York Medical College, Maria Fareri Children's Hospital, Valhalla, NY, 10595, USA; Corresponding author.Division of Pediatric Surgery, New York Medical College, Maria Fareri Children's Hospital, Valhalla, NY, 10595, USADivision of Pediatric Infectious Diseases, New York Medical College, Maria Fareri Children's Hospital, Valhalla, NY, 10595, USADivision of Pathology, New York Medical College, Maria Fareri Children's Hospital, Valhalla, NY, 10595, USADivision of Pediatric Surgery, New York Medical College, Maria Fareri Children's Hospital, Valhalla, NY, 10595, USADivision of Pediatric Surgery, New York Medical College, Maria Fareri Children's Hospital, Valhalla, NY, 10595, USAMethicillin-resistant Staphylococcus aureus (MRSA) is commonly isolated from complex intra-abdominal infections. There have been reports of MRSA isolates from various abdominal infections such as diverticulitis, spontaneous bacterial peritonitis and infected peritoneal dialysis catheters. However, there has been no report of MRSA infection related to appendicitis.We present the first case series of MRSA isolated from the abdominal fluid of two patients presenting with appendicitis and managed with laparoscopic appendectomy. Both patients were found to have MRSA isolates from the peritoneal fluid culture.The two patients underwent successful laparoscopic appendectomy and were discharged on appropriate antibiotic coverage for MRSA to complete the course of treatment.Multiple strategies have been involved to manage MRSA infection. Appropriate targeted therapy with source control remains the mainstay of intra-abdominal infections. We present two cases with MRSA isolates from the peritoneal fluid of patients with acute appendicitis. This finding highlights the importance of obtaining intra-operative cultures during appendectomies to guide post-operative antibiotic therapy. Appropriate antimicrobial therapy is the mainstay of treating these infections and preventing the emergence of multi-drug resistant organisms. Keywords: MRSA, MRSA appendicitis, Intra-operative peritoneal cultureshttp://www.sciencedirect.com/science/article/pii/S2213576617303391 |
| spellingShingle | Aditya Safaya Morgan Stockberger Karl I. Li Guiqing Wang Seunghwan Pee Gustavo Stringel Methicillin-resistant Staphylococcus aureus appendicitis Journal of Pediatric Surgery Case Reports |
| title | Methicillin-resistant Staphylococcus aureus appendicitis |
| title_full | Methicillin-resistant Staphylococcus aureus appendicitis |
| title_fullStr | Methicillin-resistant Staphylococcus aureus appendicitis |
| title_full_unstemmed | Methicillin-resistant Staphylococcus aureus appendicitis |
| title_short | Methicillin-resistant Staphylococcus aureus appendicitis |
| title_sort | methicillin resistant staphylococcus aureus appendicitis |
| url | http://www.sciencedirect.com/science/article/pii/S2213576617303391 |
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