ML364 exerts the broad-spectrum antivirulence effect by interfering with the bacterial quorum sensing system

Antivirulence strategy has been developed as a nontraditional therapy which would engender a lower evolutionary pressure toward the development of antimicrobial resistance. However, the majority of the antivirulence agents currently in development could not meet clinical needs due to their narrow an...

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Hlavní autoři: Youwen Zhang, Limin Dong, Lang Sun, Xinxin Hu, Xiukun Wang, Tongying Nie, Xue Li, Penghe Wang, Pengbo Pang, Jing Pang, Xi Lu, Kaihu Yao, Xuefu You
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2022-12-01
Edice:Frontiers in Microbiology
Témata:
On-line přístup:https://www.frontiersin.org/articles/10.3389/fmicb.2022.980217/full