Functional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming

Functional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming

The axolotl (Ambystoma mexicanum) is a caudate amphibian, which has an extraordinary ability to restore a wide variety of damaged structures by a process denominated epimorphosis. While the origin and potentiality of progenitor cells that take part during epimorphic regeneration are known to some ex...

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Bibliographic Details
Main Authors: Hugo Varela-Rodríguez, Diana G. Abella-Quintana, Annie Espinal-Centeno, Luis Varela-Rodríguez, David Gomez-Zepeda, Juan Caballero-Pérez, Paola L. García-Medel, Luis G. Brieba, José J. Ordaz-Ortiz, Alfredo Cruz-Ramirez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Lin28
let-7
epimorphic regeneration
axolotl (Ambystoma mexicanum)
metabolic reprogramming
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.562940/full

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