Antifungal Drugs

Antifungal Drugs

We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-<span style="font-variant: small-caps;">d</span>-glucan synthase, lanosterol 14-&...

Full description

Bibliographic Details
Main Authors:	Jiří Houšť, Jaroslav Spížek, Vladimír Havlíček
Format:	Article
Language:	English
Published:	MDPI AG 2020-03-01
Series:	Metabolites
Subjects:	antifungal drugs amphotericin b flucytosine triazoles echinocandins invasive fungal infections resistance siderophores
Online Access:	https://www.mdpi.com/2218-1989/10/3/106

Similar Items

New Horizons in Antifungal Therapy
by: Kaila M. Pianalto, et al.
Published: (2016-10-01)

Therapeutic Drug Monitoring of Antifungal Agents in Critically Ill Patients: Is There a Need for Dose Optimisation?
by: Daniela Baracaldo-Santamaría, et al.
Published: (2022-05-01)

Antifungal Susceptibility of <i>Saccharomyces cerevisiae</i> Isolated from Clinical Specimens
by: Aleksandra Górzyńska, et al.
Published: (2024-03-01)

Adverse Effects Associated With Currently Commonly Used Antifungal Agents: A Network Meta-Analysis and Systematic Review
by: Yan-Li Yang, et al.
Published: (2021-10-01)

Fungicidal versus fungistatic therapy of invasive Candida infection in non-neutropenic adults: a meta-analysis
by: Anand Kumar, et al.
Published: (2018-04-01)

Molecular identification, antifungal susceptibility, and resistance mechanisms of pathogenic yeasts from the China antifungal resistance surveillance trial (CARST-fungi) study
by: Qiqi Wang, et al.
Published: (2022-10-01)

Multicenter Study of Susceptibility of Aspergillus Species Isolated from Iranian University Hospitals to Seven Antifungal Agents
by: Parisa Badiee, et al.
Published: (2022-06-01)

THE IMPACT OF ANTIFUNGALS ON TOLL-LIKE RECEPTORS
by: Mircea Radu Mihu, et al.
Published: (2014-03-01)

Role of Antifungal Combinations in Difficult to Treat <i>Candida</i> Infections
by: Roxana G. Vitale
Published: (2021-09-01)

Prevalence of cryptococcal meningitis among people living with human immuno-deficiency virus and predictors of mortality in adults on induction therapy in Africa: A systematic review and meta-analysis
by: Seke G. Y. Muzazu, et al.
Published: (2022-09-01)

Epidemiological and Clinical Characteristics, Antifungal Susceptibility, and MLST-Based Genetic Analysis of <i>Cryptococcus</i> Isolates in Southern Taiwan in 2013–2020
by: Yi-Chun Chen, et al.
Published: (2022-03-01)

The Elevated Endogenous Reactive Oxygen Species Contribute to the Sensitivity of the Amphotericin B-Resistant Isolate of Aspergillus flavus to Triazoles and Echinocandins
by: Tianyu Liang, et al.
Published: (2021-08-01)

A Review of Antifungals and their Mono- and Combination- therapy in the Treatment of Invasive Fungal Infections
by: Amir Arastefar, et al.
Published: (2016-11-01)

Antifungal Prophylaxis in Solid Organ Transplant Recipients
by: Şebnem ŞENOL, et al.
Published: (2015-12-01)

Editorial: Synergistic therapy for invasive fungal infection
by: Sunil S. Menghani, et al.
Published: (2023-07-01)

Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine
by: Line Storm, et al.
Published: (2014-10-01)

Clinical and epidemiological aspects of Candidemia in eight medical centers in the state of Parana, Brazil: Parana Candidemia Network
by: Carla Sakuma de Oliveira, et al.
Published: (2021-01-01)

Treatment of Invasive Candidiasis: A Narrative Review
by: Ronen Ben-Ami
Published: (2018-08-01)

Clinical Uses of Inhaled Antifungals for Invasive Pulmonary Fungal Disease: Promises and Challenges
by: Nancy N. Vuong, et al.
Published: (2023-04-01)

REFRACTORY FUNGAL VAGINITIS TREATED BY TOPICAL AMPHOTERICIN B. Review
by: Falah Hasan Obayes AL-Khikani
Published: (2020-06-01)

Antifungals and Drug Resistance
by: Chowdhury Mobaswar Hossain, et al.
Published: (2022-10-01)

Antifungals: From Pharmacokinetics to Clinical Practice
by: Anália Carmo, et al.
Published: (2023-05-01)

Navigating the New Reality: A Review of the Epidemiological, Clinical, and Microbiological Characteristics of <i>Candida auris</i>, with a Focus on Children
by: Liat Ashkenazi-Hoffnung, et al.
Published: (2023-01-01)

A 27-year-old man with headache, fever, limb weakness and inarticulate speech
by: CUI Li-ying, et al.
Published: (2013-01-01)

Comparison of amphotericin B deoxycholate in combination with either flucytosine or fluconazole, and voriconazole plus flucytosine for the treatment of HIV-associated cryptococcal meningitis: a prospective multicenter study in China
by: Ting Zhao, et al.
Published: (2022-08-01)

A 27-year-old man with headache, fever, limb weakness and inarticulate speech
by: Xiu-li LI, et al.
Published: (2013-01-01)

AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial
by: David S. Lawrence, et al.
Published: (2018-11-01)

Use of Antifungals and Outcomes Among Inpatients at Risk of Invasive Aspergillosis or Mucormycosis in the USA: A Retrospective Cohort Study
by: Katherine Stull, et al.
Published: (2019-10-01)

Editorial: Antifungal Pipeline: Build It Strong; Build It Better!
by: John R. Perfect, et al.
Published: (2022-03-01)

Factors influencing recovery in patients with hemoblastoses and candidemia
by: G A Klyasova, et al.
Published: (2015-07-01)

Review on Current Status of Echinocandins Use
by: Martyna Mroczyńska, et al.
Published: (2020-05-01)

Candida Antifungal Resistance and Therapeutic Approach
by: Francisca Vieira, et al.
Published: (2017-08-01)

Candida Antifungal Resistance and Therapeutic Approach
by: Francisca Vieira, et al.
Published: (2017-07-01)

Induction-phase treatment costs for cryptococcal meningitis in high HIV-burden African countries: New opportunities with lower costs [version 2; peer review: 2 approved, 1 approved with reservations]
by: Amir Shroufi, et al.
Published: (2022-03-01)

Induction-phase treatment costs for cryptococcal meningitis in high HIV-burden African countries: New opportunities with lower costs [version 3; peer review: 3 approved]
by: Amir Shroufi, et al.
Published: (2022-06-01)

Prescribing Pattern of Antifungal Medications at a Tertiary Care Hospital in Oman
by: Khalid A. Al Balushi, et al.
Published: (2016-12-01)

In Vitro Interaction and Killing-Kinetics of Amphotericin B Combined with Anidulafungin or Caspofungin against <i>Candida auris</i>
by: Unai Caballero, et al.
Published: (2021-08-01)

Drug-Resistant Fungi: An Emerging Challenge Threatening Our Limited Antifungal Armamentarium
by: Amir Arastehfar, et al.
Published: (2020-12-01)

Clinical Profile of 24 AIDS Patients with Cryptococcal Meningitis in the HAART Era: A Report from an Infectious Diseases Tertiary Hospital in Western Romania
by: Iosif Marincu, et al.
Published: (2021-12-01)

Immunotherapy and Antifungal Drugs of Candidiasis: Achievements and Challenges
by: leili Aghebati-Maleki, et al.
Published: (2021-10-01)