Antimicrobial activity of the lozenge with garlic bulb powder
According the tested antimicrobial activity of constituents and their chemical characteristics, a new formulation of oral antiseptic was made based on garlic bulb powder and its active principles with strong antimicrobial activity against wide range of bacteria and fungi. The antimicrobial activi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Association of Chemical Engineers of Serbia
2011-01-01
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| Series: | Hemijska Industrija |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0367-598X/2011/0367-598X1100048K.pdf |
| _version_ | 1811321565168533504 |
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| author | Kundaković Tatjana D. Ćirić Ana D. Soković Marina D. Milenković Marina T. Nikolić Vesna D. Nikolic Goran S. |
| author_facet | Kundaković Tatjana D. Ćirić Ana D. Soković Marina D. Milenković Marina T. Nikolić Vesna D. Nikolic Goran S. |
| author_sort | Kundaković Tatjana D. |
| collection | DOAJ |
| description | According the tested antimicrobial activity of constituents and their chemical characteristics, a new formulation of oral antiseptic was made based on garlic bulb powder and its active principles with strong antimicrobial activity against wide range of bacteria and fungi. The antimicrobial activity of garlic bulb powder, allicin and the lozenge with 15% of garlic powder was tested using broth microdilution method. The tested garlic powder, as well lozenge has shown very high antimicrobial activity with MIC 1.25-5.00 mg/ml, and 1.87-7.50 mg/ml, respectively. The major compound allicin was highly active in very low concentration. Minimal inhibitory concentration of allicin was from 6.25-12.50 μg/ml for antibacterial activity and 0.4 μg/ml for antifungal activity. Those concentrations are comparable with concentration of commercially available antibiotics and fungicides. The formulation of an antiseptic with herbal constituents, high antibacterial and antifungal activity and pleasant taste could be an alternative to classical pharmaceutical oral antiseptics. |
| first_indexed | 2024-04-13T13:20:06Z |
| format | Article |
| id | doaj.art-cf9f22ad55b6488e8ba2f8c6fa328a60 |
| institution | Directory Open Access Journal |
| issn | 0367-598X |
| language | English |
| last_indexed | 2024-04-13T13:20:06Z |
| publishDate | 2011-01-01 |
| publisher | Association of Chemical Engineers of Serbia |
| record_format | Article |
| series | Hemijska Industrija |
| spelling | doaj.art-cf9f22ad55b6488e8ba2f8c6fa328a602022-12-22T02:45:21ZengAssociation of Chemical Engineers of SerbiaHemijska Industrija0367-598X2011-01-0165560761010.2298/HEMIND110414048KAntimicrobial activity of the lozenge with garlic bulb powderKundaković Tatjana D.Ćirić Ana D.Soković Marina D.Milenković Marina T.Nikolić Vesna D.Nikolic Goran S.According the tested antimicrobial activity of constituents and their chemical characteristics, a new formulation of oral antiseptic was made based on garlic bulb powder and its active principles with strong antimicrobial activity against wide range of bacteria and fungi. The antimicrobial activity of garlic bulb powder, allicin and the lozenge with 15% of garlic powder was tested using broth microdilution method. The tested garlic powder, as well lozenge has shown very high antimicrobial activity with MIC 1.25-5.00 mg/ml, and 1.87-7.50 mg/ml, respectively. The major compound allicin was highly active in very low concentration. Minimal inhibitory concentration of allicin was from 6.25-12.50 μg/ml for antibacterial activity and 0.4 μg/ml for antifungal activity. Those concentrations are comparable with concentration of commercially available antibiotics and fungicides. The formulation of an antiseptic with herbal constituents, high antibacterial and antifungal activity and pleasant taste could be an alternative to classical pharmaceutical oral antiseptics.http://www.doiserbia.nb.rs/img/doi/0367-598X/2011/0367-598X1100048K.pdfAllium sativumallicinlozengeantimicrobial activity |
| spellingShingle | Kundaković Tatjana D. Ćirić Ana D. Soković Marina D. Milenković Marina T. Nikolić Vesna D. Nikolic Goran S. Antimicrobial activity of the lozenge with garlic bulb powder Hemijska Industrija Allium sativum allicin lozenge antimicrobial activity |
| title | Antimicrobial activity of the lozenge with garlic bulb powder |
| title_full | Antimicrobial activity of the lozenge with garlic bulb powder |
| title_fullStr | Antimicrobial activity of the lozenge with garlic bulb powder |
| title_full_unstemmed | Antimicrobial activity of the lozenge with garlic bulb powder |
| title_short | Antimicrobial activity of the lozenge with garlic bulb powder |
| title_sort | antimicrobial activity of the lozenge with garlic bulb powder |
| topic | Allium sativum allicin lozenge antimicrobial activity |
| url | http://www.doiserbia.nb.rs/img/doi/0367-598X/2011/0367-598X1100048K.pdf |
| work_keys_str_mv | AT kundakovictatjanad antimicrobialactivityofthelozengewithgarlicbulbpowder AT ciricanad antimicrobialactivityofthelozengewithgarlicbulbpowder AT sokovicmarinad antimicrobialactivityofthelozengewithgarlicbulbpowder AT milenkovicmarinat antimicrobialactivityofthelozengewithgarlicbulbpowder AT nikolicvesnad antimicrobialactivityofthelozengewithgarlicbulbpowder AT nikolicgorans antimicrobialactivityofthelozengewithgarlicbulbpowder |