Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection
Cerebral ventricular infection (CVI) is one of the most dangerous complications in neurosurgery because of its high mortality and disability rates. Few studies have examined the application of neuroendoscopic surgical techniques (NESTs) to assess and treat CVI. This multicenter, retrospective study...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Neural Regeneration Research |
| Subjects: | |
| Online Access: | http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=12;spage=2095;epage=2103;aulast=Guan |
| _version_ | 1818246831856943104 |
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| author | Feng Guan Wei-Cheng Peng Hui Huang Zu-Yuan Ren Zhen-Yu Wang Ji-Di Fu Ying-Bin Li Feng-Qi Cui Bin Dai Guang-Tong Zhu Zhi-Yong Xiao Bei-Bei Mao Zhi-Qiang Hu |
| author_facet | Feng Guan Wei-Cheng Peng Hui Huang Zu-Yuan Ren Zhen-Yu Wang Ji-Di Fu Ying-Bin Li Feng-Qi Cui Bin Dai Guang-Tong Zhu Zhi-Yong Xiao Bei-Bei Mao Zhi-Qiang Hu |
| author_sort | Feng Guan |
| collection | DOAJ |
| description | Cerebral ventricular infection (CVI) is one of the most dangerous complications in neurosurgery because of its high mortality and disability rates. Few studies have examined the application of neuroendoscopic surgical techniques (NESTs) to assess and treat CVI. This multicenter, retrospective study was conducted using clinical data of 32 patients with CVI who were assessed and treated by NESTs in China. The patients included 20 men and 12 women with a mean age of 42.97 years. NESTs were used to obliterate intraventricular debris and pus, fenestrate or incise the intraventricular compartment and reconstruct cerebrospinal fluid circulation, and remove artificial material. Intraventricular irrigation with antibiotic saline was applied after neuroendoscopic surgery (NES). Secondary hydrocephalus was treated by endoscopic third ventriculostomy or a ventriculoperitoneal shunt. Neuroendoscopic findings of CVI were used to classify patients into Grade I (n = 3), Grade II (n = 13), Grade III (n = 10), and Grade IV (n = 6) CVI. The three patients with grade I CVI underwent one NES, the 23 patients with grade II/III CVI underwent two NESs, and patients with grade IV CVI underwent two (n = 3) or three (n = 3) NESs. The imaging features and grades of neuroendoscopy results were positively related to the number of neurosurgical endoscopic procedures. Two patients died of multiple organ failure and the other 30 patients fully recovered. Among the 26 patients with secondary hydrocephalus, 18 received ventriculoperitoneal shunt and 8 underwent endoscopic third ventriculostomy. There were no recurrences of CVI during the 6- to 76-month follow-up after NES. Application of NESTs is an innovative method to assess and treat CVI, and its neuroendoscopic classification provides an objective, comprehensive assessment of CVI. The study trial was approved by the Institutional Review Board of Beijing Shijitan Hospital, Capital Medical University, China. |
| first_indexed | 2024-12-12T14:55:04Z |
| format | Article |
| id | doaj.art-cfa06a54dad54c5cb1d1c2b0be364876 |
| institution | Directory Open Access Journal |
| issn | 1673-5374 |
| language | English |
| last_indexed | 2024-12-12T14:55:04Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Neural Regeneration Research |
| spelling | doaj.art-cfa06a54dad54c5cb1d1c2b0be3648762022-12-22T00:20:56ZengWolters Kluwer Medknow PublicationsNeural Regeneration Research1673-53742019-01-0114122095210310.4103/1673-5374.262591Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infectionFeng GuanWei-Cheng PengHui HuangZu-Yuan RenZhen-Yu WangJi-Di FuYing-Bin LiFeng-Qi CuiBin DaiGuang-Tong ZhuZhi-Yong XiaoBei-Bei MaoZhi-Qiang HuCerebral ventricular infection (CVI) is one of the most dangerous complications in neurosurgery because of its high mortality and disability rates. Few studies have examined the application of neuroendoscopic surgical techniques (NESTs) to assess and treat CVI. This multicenter, retrospective study was conducted using clinical data of 32 patients with CVI who were assessed and treated by NESTs in China. The patients included 20 men and 12 women with a mean age of 42.97 years. NESTs were used to obliterate intraventricular debris and pus, fenestrate or incise the intraventricular compartment and reconstruct cerebrospinal fluid circulation, and remove artificial material. Intraventricular irrigation with antibiotic saline was applied after neuroendoscopic surgery (NES). Secondary hydrocephalus was treated by endoscopic third ventriculostomy or a ventriculoperitoneal shunt. Neuroendoscopic findings of CVI were used to classify patients into Grade I (n = 3), Grade II (n = 13), Grade III (n = 10), and Grade IV (n = 6) CVI. The three patients with grade I CVI underwent one NES, the 23 patients with grade II/III CVI underwent two NESs, and patients with grade IV CVI underwent two (n = 3) or three (n = 3) NESs. The imaging features and grades of neuroendoscopy results were positively related to the number of neurosurgical endoscopic procedures. Two patients died of multiple organ failure and the other 30 patients fully recovered. Among the 26 patients with secondary hydrocephalus, 18 received ventriculoperitoneal shunt and 8 underwent endoscopic third ventriculostomy. There were no recurrences of CVI during the 6- to 76-month follow-up after NES. Application of NESTs is an innovative method to assess and treat CVI, and its neuroendoscopic classification provides an objective, comprehensive assessment of CVI. The study trial was approved by the Institutional Review Board of Beijing Shijitan Hospital, Capital Medical University, China.http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=12;spage=2095;epage=2103;aulast=Guannerve regeneration; neuroendoscopy; surgery; cerebral ventricular infection; assessment; treatment; hydrocephalus; irrigation; neural regeneration |
| spellingShingle | Feng Guan Wei-Cheng Peng Hui Huang Zu-Yuan Ren Zhen-Yu Wang Ji-Di Fu Ying-Bin Li Feng-Qi Cui Bin Dai Guang-Tong Zhu Zhi-Yong Xiao Bei-Bei Mao Zhi-Qiang Hu Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection Neural Regeneration Research nerve regeneration; neuroendoscopy; surgery; cerebral ventricular infection; assessment; treatment; hydrocephalus; irrigation; neural regeneration |
| title | Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection |
| title_full | Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection |
| title_fullStr | Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection |
| title_full_unstemmed | Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection |
| title_short | Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection |
| title_sort | application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection |
| topic | nerve regeneration; neuroendoscopy; surgery; cerebral ventricular infection; assessment; treatment; hydrocephalus; irrigation; neural regeneration |
| url | http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=12;spage=2095;epage=2103;aulast=Guan |
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