Antisense miR-7 Impairs Insulin Expression in Developing Pancreas and in Cultured Pancreatic Buds

Antisense miR-7 Impairs Insulin Expression in Developing Pancreas and in Cultured Pancreatic Buds

MicroRNAs regulate gene expression by inhibiting translation or inducing target mRNA degradation. MicroRNAs regulate organ differentiation and embryonic development, including pancreatic specification and islet function. We showed previously that miR-7 is highly expressed in human pancreatic fetal a...

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Bibliographic Details
Main Authors: Margarita Nieto, Pedro Hevia, Enrique Garcia, Dagmar Klein, Silvia Alvarez-Cubela, Valia Bravo-Egana, Samuel Rosero, R. Damaris Molano, Nancy Vargas, Camillo Ricordi, Antonello Pileggi, Juan Diez, Juan Domínguez-Bendala, Ricardo L. Pastori Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2012-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X612521

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