Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review
The design of a scaffold of bone tissue engineering plays an important role in ensuring cell viability and cell growth. Therefore, it is a necessity to produce an ideal scaffold by predicting and simulating the properties of the scaffold. Hence, the computational method should be adopted since it ha...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/13/10/1584 |
| _version_ | 1797534125020676096 |
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| author | Nur Syahirah Mustafa Nor Hasrul Akhmal Sudin Izman Mat Hussin Ab Talib Ashrul Ishak Mohamad Shaiful Mohd Nazri Bin Omar Nor Zaiazmin Yahaya Suhaimi Illias |
| author_facet | Nur Syahirah Mustafa Nor Hasrul Akhmal Sudin Izman Mat Hussin Ab Talib Ashrul Ishak Mohamad Shaiful Mohd Nazri Bin Omar Nor Zaiazmin Yahaya Suhaimi Illias |
| author_sort | Nur Syahirah Mustafa |
| collection | DOAJ |
| description | The design of a scaffold of bone tissue engineering plays an important role in ensuring cell viability and cell growth. Therefore, it is a necessity to produce an ideal scaffold by predicting and simulating the properties of the scaffold. Hence, the computational method should be adopted since it has a huge potential to be used in the implementation of the scaffold of bone tissue engineering. To explore the field of computational method in the area of bone tissue engineering, this paper provides an overview of the usage of a computational method in designing a unit cell of bone tissue engineering scaffold. In order to design a unit cell of the scaffold, we discussed two categories of unit cells that can be used to design a feasible scaffold, which are non-parametric and parametric designs. These designs were later described and being categorised into multiple types according to their characteristics, such as circular structures and Triply Periodic Minimal Surface (TPMS) structures. The advantages and disadvantages of these designs were discussed. Moreover, this paper also represents some software that was used in simulating and designing the bone tissue scaffold. The challenges and future work recommendations had also been included in this paper. |
| first_indexed | 2024-03-10T11:25:13Z |
| format | Article |
| id | doaj.art-cfa4de436dd9411484016151739dc52f |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T11:25:13Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-cfa4de436dd9411484016151739dc52f2023-11-21T19:46:18ZengMDPI AGPolymers2073-43602021-05-011310158410.3390/polym13101584Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A ReviewNur Syahirah Mustafa0Nor Hasrul Akhmal1Sudin Izman2Mat Hussin Ab Talib3Ashrul Ishak Mohamad Shaiful4Mohd Nazri Bin Omar5Nor Zaiazmin Yahaya6Suhaimi Illias7Faculty of Engineering, School of Mechanical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor 81310, MalaysiaFaculty of Engineering, School of Mechanical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor 81310, MalaysiaFaculty of Engineering, School of Mechanical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor 81310, MalaysiaFaculty of Engineering, School of Mechanical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor 81310, MalaysiaFaculty of Mechanical Engineering Technology, Universiti Malaysia Perlis, Arau 02600, MalaysiaFaculty of Mechanical Engineering Technology, Universiti Malaysia Perlis, Arau 02600, MalaysiaFaculty of Mechanical Engineering Technology, Universiti Malaysia Perlis, Arau 02600, MalaysiaFaculty of Mechanical Engineering Technology, Universiti Malaysia Perlis, Arau 02600, MalaysiaThe design of a scaffold of bone tissue engineering plays an important role in ensuring cell viability and cell growth. Therefore, it is a necessity to produce an ideal scaffold by predicting and simulating the properties of the scaffold. Hence, the computational method should be adopted since it has a huge potential to be used in the implementation of the scaffold of bone tissue engineering. To explore the field of computational method in the area of bone tissue engineering, this paper provides an overview of the usage of a computational method in designing a unit cell of bone tissue engineering scaffold. In order to design a unit cell of the scaffold, we discussed two categories of unit cells that can be used to design a feasible scaffold, which are non-parametric and parametric designs. These designs were later described and being categorised into multiple types according to their characteristics, such as circular structures and Triply Periodic Minimal Surface (TPMS) structures. The advantages and disadvantages of these designs were discussed. Moreover, this paper also represents some software that was used in simulating and designing the bone tissue scaffold. The challenges and future work recommendations had also been included in this paper.https://www.mdpi.com/2073-4360/13/10/1584numerical analysiscomputational methodtissue engineering scaffold designmechanical strengthsimulation software |
| spellingShingle | Nur Syahirah Mustafa Nor Hasrul Akhmal Sudin Izman Mat Hussin Ab Talib Ashrul Ishak Mohamad Shaiful Mohd Nazri Bin Omar Nor Zaiazmin Yahaya Suhaimi Illias Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review Polymers numerical analysis computational method tissue engineering scaffold design mechanical strength simulation software |
| title | Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review |
| title_full | Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review |
| title_fullStr | Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review |
| title_full_unstemmed | Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review |
| title_short | Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review |
| title_sort | application of computational method in designing a unit cell of bone tissue engineering scaffold a review |
| topic | numerical analysis computational method tissue engineering scaffold design mechanical strength simulation software |
| url | https://www.mdpi.com/2073-4360/13/10/1584 |
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