Importance of residue 248 in Escherichia coli RNase P RNA mediated cleavage

Importance of residue 248 in Escherichia coli RNase P RNA mediated cleavage

Abstract tRNA genes are transcribed as precursors and RNase P generates the matured 5' end of tRNAs. It has been suggested that residue − 1 (the residue immediately 5ʹ of the scissile bond) in the pre-tRNA interacts with the well-conserved bacterial RNase P RNA (RPR) residue A248 (Escherichia c...

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Bibliographic Details
Main Authors: Guanzhong Mao, Abhishek S. Srivastava, Shiying Wu, David Kosek, Leif A. Kirsebom
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41203-4

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