BINOL as a chiral element in mechanically interlocked molecules
In this minireview we present the use of the axially chiral 1,1'-binaphthyl-2,2'-diol (BINOL) unit as a stereogenic element in mechanically interlocked molecules (MIMs). We describe the synthesis and properties of such BINOL-based chiral MIMs, together with their use in further diastereose...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2022-05-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.18.53 |
| _version_ | 1828528025164054528 |
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| author | Matthias Krajnc Jochen Niemeyer |
| author_facet | Matthias Krajnc Jochen Niemeyer |
| author_sort | Matthias Krajnc |
| collection | DOAJ |
| description | In this minireview we present the use of the axially chiral 1,1'-binaphthyl-2,2'-diol (BINOL) unit as a stereogenic element in mechanically interlocked molecules (MIMs). We describe the synthesis and properties of such BINOL-based chiral MIMs, together with their use in further diastereoselective modifications, their application in asymmetric catalysis, and their use in stereoselective chemosensing. Given the growing importance of mechanically interlocked molecules and the key advantages of the privileged chiral BINOL backbone, we believe that this research area will continue to grow and deliver many useful applications in the future. |
| first_indexed | 2024-12-11T21:46:28Z |
| format | Article |
| id | doaj.art-cfad2cd17bc24207bfae776ca2d666c8 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-11T21:46:28Z |
| publishDate | 2022-05-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-cfad2cd17bc24207bfae776ca2d666c82022-12-22T00:49:36ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972022-05-0118150852310.3762/bjoc.18.531860-5397-18-53BINOL as a chiral element in mechanically interlocked moleculesMatthias Krajnc0Jochen Niemeyer1Faculty of Chemistry (Organic Chemistry) and Centre of Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitätsstr. 7, 45141 Essen, GermanyFaculty of Chemistry (Organic Chemistry) and Centre of Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitätsstr. 7, 45141 Essen, GermanyIn this minireview we present the use of the axially chiral 1,1'-binaphthyl-2,2'-diol (BINOL) unit as a stereogenic element in mechanically interlocked molecules (MIMs). We describe the synthesis and properties of such BINOL-based chiral MIMs, together with their use in further diastereoselective modifications, their application in asymmetric catalysis, and their use in stereoselective chemosensing. Given the growing importance of mechanically interlocked molecules and the key advantages of the privileged chiral BINOL backbone, we believe that this research area will continue to grow and deliver many useful applications in the future.https://doi.org/10.3762/bjoc.18.53axial chiralitybinolcatenanesinterlocked moleculesrotaxanes |
| spellingShingle | Matthias Krajnc Jochen Niemeyer BINOL as a chiral element in mechanically interlocked molecules Beilstein Journal of Organic Chemistry axial chirality binol catenanes interlocked molecules rotaxanes |
| title | BINOL as a chiral element in mechanically interlocked molecules |
| title_full | BINOL as a chiral element in mechanically interlocked molecules |
| title_fullStr | BINOL as a chiral element in mechanically interlocked molecules |
| title_full_unstemmed | BINOL as a chiral element in mechanically interlocked molecules |
| title_short | BINOL as a chiral element in mechanically interlocked molecules |
| title_sort | binol as a chiral element in mechanically interlocked molecules |
| topic | axial chirality binol catenanes interlocked molecules rotaxanes |
| url | https://doi.org/10.3762/bjoc.18.53 |
| work_keys_str_mv | AT matthiaskrajnc binolasachiralelementinmechanicallyinterlockedmolecules AT jochenniemeyer binolasachiralelementinmechanicallyinterlockedmolecules |