Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> during Early Macrophage Infection

Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> during Early Macrophage Infection

ABSTRACT Nutrient acquisition from the host environment is crucial for the survival of intracellular pathogens, but conceptual and technical challenges limit our knowledge of pathogen diets. To overcome some of these technical roadblocks, we exploited an experimentally accessible model for early inf...

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Bibliographic Details
Main Authors: Michael Zimmermann, Maria Kogadeeva, Martin Gengenbacher, Gayle McEwen, Hans-Joachim Mollenkopf, Nicola Zamboni, Stefan Hugo Ernst Kaufmann, Uwe Sauer
Format: Article
Language:English
Published: American Society for Microbiology 2017-08-01
Series:mSystems
Subjects:
Mycobacterium tuberculosis
host-pathogen interactions
metabolism
systems biology
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00057-17

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