Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?
Transient cortical blindness (TCB) is a well known but rare complication of administration of contrast agent. In this case report, we present a 53-year-old woman who is a follow-up case of sarcoidosis and developed TCB with focal neurological symptoms following contrast-enhanced computed tomography...
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Wolters Kluwer Medknow Publications
2011-01-01
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Series: | Annals of Indian Academy of Neurology |
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Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=4;spage=298;epage=300;aulast=Suri |
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author | Vinit Suri Ritu Agarwal Nilesh Jadhao Gulshan K Ahuja |
author_facet | Vinit Suri Ritu Agarwal Nilesh Jadhao Gulshan K Ahuja |
author_sort | Vinit Suri |
collection | DOAJ |
description | Transient cortical blindness (TCB) is a well known but rare complication of administration of contrast agent. In this case report, we present a 53-year-old woman who is a follow-up case of sarcoidosis and developed TCB with focal neurological symptoms following contrast-enhanced computed tomography scan. Magnetic resonance imaging revealed bilateral T2/Flair hyperintensities in parieto-occipital, high frontal, and cerebellar hemispheres with involvement of corpus callosum. Clinically and radiologically patient improved significantly in 4 days. The exact mechanism is still speculative and its possible relationship with posterior reversible encephalopathy syndrome is briefly discussed. The patient′s symptoms were presumed to be exacerbated by presence of hypertension, underlying autoimmune disorder, sepsis, and high osmolality of contrast agent. Though there is no definite evidence to suggest that a certain treatment regimen improves the natural history of this disease but control of risk factors can possibly prevent this rare but devastating complication. |
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institution | Directory Open Access Journal |
issn | 0972-2327 1998-3549 |
language | English |
last_indexed | 2024-12-16T07:34:57Z |
publishDate | 2011-01-01 |
publisher | Wolters Kluwer Medknow Publications |
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series | Annals of Indian Academy of Neurology |
spelling | doaj.art-cfb48ca25a53413fbc37121636ad0d4c2022-12-21T22:39:15ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492011-01-0114429830010.4103/0972-2327.91956Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?Vinit SuriRitu AgarwalNilesh JadhaoGulshan K AhujaTransient cortical blindness (TCB) is a well known but rare complication of administration of contrast agent. In this case report, we present a 53-year-old woman who is a follow-up case of sarcoidosis and developed TCB with focal neurological symptoms following contrast-enhanced computed tomography scan. Magnetic resonance imaging revealed bilateral T2/Flair hyperintensities in parieto-occipital, high frontal, and cerebellar hemispheres with involvement of corpus callosum. Clinically and radiologically patient improved significantly in 4 days. The exact mechanism is still speculative and its possible relationship with posterior reversible encephalopathy syndrome is briefly discussed. The patient′s symptoms were presumed to be exacerbated by presence of hypertension, underlying autoimmune disorder, sepsis, and high osmolality of contrast agent. Though there is no definite evidence to suggest that a certain treatment regimen improves the natural history of this disease but control of risk factors can possibly prevent this rare but devastating complication.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=4;spage=298;epage=300;aulast=SuriSarcoidosisposterior reversible encephalopathy syndromecontrastcortical blindness |
spellingShingle | Vinit Suri Ritu Agarwal Nilesh Jadhao Gulshan K Ahuja Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome? Annals of Indian Academy of Neurology Sarcoidosis posterior reversible encephalopathy syndrome contrast cortical blindness |
title | Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome? |
title_full | Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome? |
title_fullStr | Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome? |
title_full_unstemmed | Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome? |
title_short | Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome? |
title_sort | cortical blindness after contrast enhanced ct scan in a patient of sarcoidosis is it related to posterior reversible encephalopathy syndrome |
topic | Sarcoidosis posterior reversible encephalopathy syndrome contrast cortical blindness |
url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=4;spage=298;epage=300;aulast=Suri |
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