Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?

Transient cortical blindness (TCB) is a well known but rare complication of administration of contrast agent. In this case report, we present a 53-year-old woman who is a follow-up case of sarcoidosis and developed TCB with focal neurological symptoms following contrast-enhanced computed tomography...

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Main Authors: Vinit Suri, Ritu Agarwal, Nilesh Jadhao, Gulshan K Ahuja
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=4;spage=298;epage=300;aulast=Suri
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author Vinit Suri
Ritu Agarwal
Nilesh Jadhao
Gulshan K Ahuja
author_facet Vinit Suri
Ritu Agarwal
Nilesh Jadhao
Gulshan K Ahuja
author_sort Vinit Suri
collection DOAJ
description Transient cortical blindness (TCB) is a well known but rare complication of administration of contrast agent. In this case report, we present a 53-year-old woman who is a follow-up case of sarcoidosis and developed TCB with focal neurological symptoms following contrast-enhanced computed tomography scan. Magnetic resonance imaging revealed bilateral T2/Flair hyperintensities in parieto-occipital, high frontal, and cerebellar hemispheres with involvement of corpus callosum. Clinically and radiologically patient improved significantly in 4 days. The exact mechanism is still speculative and its possible relationship with posterior reversible encephalopathy syndrome is briefly discussed. The patient′s symptoms were presumed to be exacerbated by presence of hypertension, underlying autoimmune disorder, sepsis, and high osmolality of contrast agent. Though there is no definite evidence to suggest that a certain treatment regimen improves the natural history of this disease but control of risk factors can possibly prevent this rare but devastating complication.
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spelling doaj.art-cfb48ca25a53413fbc37121636ad0d4c2022-12-21T22:39:15ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492011-01-0114429830010.4103/0972-2327.91956Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?Vinit SuriRitu AgarwalNilesh JadhaoGulshan K AhujaTransient cortical blindness (TCB) is a well known but rare complication of administration of contrast agent. In this case report, we present a 53-year-old woman who is a follow-up case of sarcoidosis and developed TCB with focal neurological symptoms following contrast-enhanced computed tomography scan. Magnetic resonance imaging revealed bilateral T2/Flair hyperintensities in parieto-occipital, high frontal, and cerebellar hemispheres with involvement of corpus callosum. Clinically and radiologically patient improved significantly in 4 days. The exact mechanism is still speculative and its possible relationship with posterior reversible encephalopathy syndrome is briefly discussed. The patient′s symptoms were presumed to be exacerbated by presence of hypertension, underlying autoimmune disorder, sepsis, and high osmolality of contrast agent. Though there is no definite evidence to suggest that a certain treatment regimen improves the natural history of this disease but control of risk factors can possibly prevent this rare but devastating complication.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=4;spage=298;epage=300;aulast=SuriSarcoidosisposterior reversible encephalopathy syndromecontrastcortical blindness
spellingShingle Vinit Suri
Ritu Agarwal
Nilesh Jadhao
Gulshan K Ahuja
Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?
Annals of Indian Academy of Neurology
Sarcoidosis
posterior reversible encephalopathy syndrome
contrast
cortical blindness
title Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?
title_full Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?
title_fullStr Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?
title_full_unstemmed Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?
title_short Cortical blindness after contrast-enhanced CT scan in a patient of sarcoidosis - Is it related to posterior reversible encephalopathy syndrome?
title_sort cortical blindness after contrast enhanced ct scan in a patient of sarcoidosis is it related to posterior reversible encephalopathy syndrome
topic Sarcoidosis
posterior reversible encephalopathy syndrome
contrast
cortical blindness
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=4;spage=298;epage=300;aulast=Suri
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AT rituagarwal corticalblindnessaftercontrastenhancedctscaninapatientofsarcoidosisisitrelatedtoposteriorreversibleencephalopathysyndrome
AT nileshjadhao corticalblindnessaftercontrastenhancedctscaninapatientofsarcoidosisisitrelatedtoposteriorreversibleencephalopathysyndrome
AT gulshankahuja corticalblindnessaftercontrastenhancedctscaninapatientofsarcoidosisisitrelatedtoposteriorreversibleencephalopathysyndrome