Inflammatory myofibroblastic tumor of the right frontal lobe
Abstract Background We aim to present an unique case of inflammatory myofibroblastic tumor (IMT) of the brain parenchyma and study the clinical presentation, imagine characteristic, intraoperative findings, and histopathology features of IMT in the brain parenchyma. Case Presentation A 36-year-old f...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-06-01
|
| Series: | Chinese Neurosurgical Journal |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41016-017-0076-5 |
| _version_ | 1819063782166495232 |
|---|---|
| author | Xuejian Wang Zhifeng Wang Yang Chen Ming Qian |
| author_facet | Xuejian Wang Zhifeng Wang Yang Chen Ming Qian |
| author_sort | Xuejian Wang |
| collection | DOAJ |
| description | Abstract Background We aim to present an unique case of inflammatory myofibroblastic tumor (IMT) of the brain parenchyma and study the clinical presentation, imagine characteristic, intraoperative findings, and histopathology features of IMT in the brain parenchyma. Case Presentation A 36-year-old female with IMT come to see doctor presented with a 3-month history of progressively worsening weakness in the left upper limb along with alalia. Serial magnetic resonance imaging studies revealed a lesion within the right frontal lobe. The lesions were locally clear boundary with peripheral tissues. A right frontotemporal craniotomy was performed and the specimens were detected by immunohistochemical staining and light microscopy. Through the microscope, the tumor was composed of large number of chronic inflammatory cells and spindle cells. From immunohistochemical stains, it demonstrated CD34 (+), SMA (+), Vimentin (+), and actin (+) were positive meanwhile S-100(-) was negative. Conclusion IMT of the right frontal lobe is a rare lesions. Surgical resection is the best and the most effective treatment. |
| first_indexed | 2024-12-21T15:20:08Z |
| format | Article |
| id | doaj.art-cfb5445bd3c448e4bcda297be85bcdac |
| institution | Directory Open Access Journal |
| issn | 2057-4967 |
| language | English |
| last_indexed | 2024-12-21T15:20:08Z |
| publishDate | 2017-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Chinese Neurosurgical Journal |
| spelling | doaj.art-cfb5445bd3c448e4bcda297be85bcdac2022-12-21T18:59:03ZengBMCChinese Neurosurgical Journal2057-49672017-06-01311410.1186/s41016-017-0076-5Inflammatory myofibroblastic tumor of the right frontal lobeXuejian Wang0Zhifeng Wang1Yang Chen2Ming Qian3Department of Neurosurgery, the Second Hospital affiliated to Nantong University, Nantong UniversityDepartment of Neurosurgery, the Second Hospital affiliated to Nantong University, Nantong UniversityDepartment of Neurosurgery, the Second Hospital affiliated to Nantong University, Nantong UniversityDepartment of Neurosurgery, the Second Hospital affiliated to Nantong University, Nantong UniversityAbstract Background We aim to present an unique case of inflammatory myofibroblastic tumor (IMT) of the brain parenchyma and study the clinical presentation, imagine characteristic, intraoperative findings, and histopathology features of IMT in the brain parenchyma. Case Presentation A 36-year-old female with IMT come to see doctor presented with a 3-month history of progressively worsening weakness in the left upper limb along with alalia. Serial magnetic resonance imaging studies revealed a lesion within the right frontal lobe. The lesions were locally clear boundary with peripheral tissues. A right frontotemporal craniotomy was performed and the specimens were detected by immunohistochemical staining and light microscopy. Through the microscope, the tumor was composed of large number of chronic inflammatory cells and spindle cells. From immunohistochemical stains, it demonstrated CD34 (+), SMA (+), Vimentin (+), and actin (+) were positive meanwhile S-100(-) was negative. Conclusion IMT of the right frontal lobe is a rare lesions. Surgical resection is the best and the most effective treatment.http://link.springer.com/article/10.1186/s41016-017-0076-5Inflammatory myofibroblastic tumor (IMT)Inflammatory pseudotumorTherapy |
| spellingShingle | Xuejian Wang Zhifeng Wang Yang Chen Ming Qian Inflammatory myofibroblastic tumor of the right frontal lobe Chinese Neurosurgical Journal Inflammatory myofibroblastic tumor (IMT) Inflammatory pseudotumor Therapy |
| title | Inflammatory myofibroblastic tumor of the right frontal lobe |
| title_full | Inflammatory myofibroblastic tumor of the right frontal lobe |
| title_fullStr | Inflammatory myofibroblastic tumor of the right frontal lobe |
| title_full_unstemmed | Inflammatory myofibroblastic tumor of the right frontal lobe |
| title_short | Inflammatory myofibroblastic tumor of the right frontal lobe |
| title_sort | inflammatory myofibroblastic tumor of the right frontal lobe |
| topic | Inflammatory myofibroblastic tumor (IMT) Inflammatory pseudotumor Therapy |
| url | http://link.springer.com/article/10.1186/s41016-017-0076-5 |
| work_keys_str_mv | AT xuejianwang inflammatorymyofibroblastictumoroftherightfrontallobe AT zhifengwang inflammatorymyofibroblastictumoroftherightfrontallobe AT yangchen inflammatorymyofibroblastictumoroftherightfrontallobe AT mingqian inflammatorymyofibroblastictumoroftherightfrontallobe |