A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes

Mucormycosis is a rare, potentially life-threatening disease that is growing during the Covid-19 pandemic. This study reports a case of an 11-year-old patient with fatal Covid-19-related pulmonary mucormicosis and diabetes mellitus with ketoacidosis. The diagnosis was set post mortem. It was based o...

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Main Authors: L. Pekova, M. Gulubova, M. Hadzhi, M. Mitev, S. Angelova
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007122000776
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author L. Pekova
M. Gulubova
M. Hadzhi
M. Mitev
S. Angelova
author_facet L. Pekova
M. Gulubova
M. Hadzhi
M. Mitev
S. Angelova
author_sort L. Pekova
collection DOAJ
description Mucormycosis is a rare, potentially life-threatening disease that is growing during the Covid-19 pandemic. This study reports a case of an 11-year-old patient with fatal Covid-19-related pulmonary mucormicosis and diabetes mellitus with ketoacidosis. The diagnosis was set post mortem. It was based on histochemical detection of the causative agent. Massive hemoptysis due to erosion of a large pulmonary vessel caused mechanical asphyxia and lethal outcome. Pulmonary mucormycosis may be highly suspected in patients with long-term Covid-19, poorly controlled diabetes mellitus with ketoacidosis, and corticosteroid therapy. Early diagnosis and treatment with Amphotericin B are potentially curative options for this invasive fungal infection and can led to better outcome.
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spelling doaj.art-cfb55083939a48d7a8050fbf73e2fbf72022-12-22T00:37:43ZengElsevierRespiratory Medicine Case Reports2213-00712022-01-0137101655A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetesL. Pekova0M. Gulubova1M. Hadzhi2M. Mitev3S. Angelova4Dept. of Infectious Diseases, Medical Faculty, Trakia University, Stara Zagora, Bulgaria; Corresponding author. Department of Infectious Diseases, Medical Faculty, Trakia University, 11 Armeyska Str., 6000, Stara Zagora, Bulgaria.Dept. of General and Clinical Pathology, Medical Faculty, Trakia University, Stara Zagora, BulgariaDept. of General and Clinical Pathology, Medical Faculty, Trakia University, Stara Zagora, BulgariaDept. of Imaging Diagnostic, Medical Faculty, Trakia University, Stara Zagora, BulgariaDept. of Microbiology, Medical Faculty, Trakia University, Stara Zagora, BulgariaMucormycosis is a rare, potentially life-threatening disease that is growing during the Covid-19 pandemic. This study reports a case of an 11-year-old patient with fatal Covid-19-related pulmonary mucormicosis and diabetes mellitus with ketoacidosis. The diagnosis was set post mortem. It was based on histochemical detection of the causative agent. Massive hemoptysis due to erosion of a large pulmonary vessel caused mechanical asphyxia and lethal outcome. Pulmonary mucormycosis may be highly suspected in patients with long-term Covid-19, poorly controlled diabetes mellitus with ketoacidosis, and corticosteroid therapy. Early diagnosis and treatment with Amphotericin B are potentially curative options for this invasive fungal infection and can led to better outcome.http://www.sciencedirect.com/science/article/pii/S2213007122000776Pulmonary mucormycosisCovid-19 infectionPediatric patientDiabetes mellitus
spellingShingle L. Pekova
M. Gulubova
M. Hadzhi
M. Mitev
S. Angelova
A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
Respiratory Medicine Case Reports
Pulmonary mucormycosis
Covid-19 infection
Pediatric patient
Diabetes mellitus
title A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_full A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_fullStr A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_full_unstemmed A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_short A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_sort case of covid 19 associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
topic Pulmonary mucormycosis
Covid-19 infection
Pediatric patient
Diabetes mellitus
url http://www.sciencedirect.com/science/article/pii/S2213007122000776
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