The Difference in Immunoglobulin G Levels Between Outpatients and Inpatients With COVID-19
Background: Coronavirus disease 2019 (COVID-19) has rapidly become a pandemic since it was first reported in late December 2019. Serological reports are of great value to medical specialists in developing health policies. The detection of Immunoglobulin G (IgG) level in COVID-19 patients can spec...
| Main Authors: | , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Qazvin University of Medical Sciences & Health Services
2022-10-01
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| Series: | The Journal of Qazvin University of Medical Sciences |
| Subjects: | |
| Online Access: | https://journal.qums.ac.ir/article-1-3259-en.html |
| Summary: | Background: Coronavirus disease 2019 (COVID-19) has rapidly become a pandemic since
it was first reported in late December 2019. Serological reports are of great value to medical
specialists in developing health policies. The detection of Immunoglobulin G (IgG) level
in COVID-19 patients can specify a preclinical infection or previous exposure to the virus.
Objective: This study aims to assess the IgG rate in patients with COVID-19.
Methods: This is a cross-sectional study on 172 patients with confirmed COVID-19 (having
positive PCR test) in Qazvin, Iran in 2020, including 86 inpatients and 86 outpatients.
In order to measure the IgG levels, the serum samples were collected 3-5 weeks after
onset of their clinical symptoms. Data were statistically analyzed in SPSS software v. 20,
considering the significance level of P<0.05.
Results: Of 172 patients, 81(94.2%) inpatients and 74(86%) outpatients tested positive for
IgG, while 5(5.8%) inpatients and 10(11.6%) outpatients tested negative for IgG. The mean
IgG level in inpatients was significantly higher than in outpatients (P<0.001) 3-5 weeks
after a positive PCR test.
Conclusion: The amounts of IgG in the sera of COVID-19 patients 3-5 weeks after the
onset of symptoms can help health care authorities develop policies and control strategies
by determining the burden of disease, monitoring the spread of disease, and estimating the
epidemiological factors. |
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| ISSN: | 1561-3666 2228-7213 |