Pretherapeutic PSMA PET-Derived Semiquantitative Parameters as Predictors of PSA Response in Patients with mCRPC Receiving [<sup>177</sup>Lu]Lu-PSMA-617 Radioligand Therapy

Objective [177Lu]Lu-prostate-specific membrane antigen (PSMA)-617 radioligand therapy (RLT) shows promise for metastatic castration-resistant prostate cancer (mCRPC) patients with positive PSMA positron emission tomography (PET) imaging. Identifying high-risk patients is crucial. We evalu...

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Main Authors: Dheeratama Siripongsatian, Attapon Jantarato, Chetsadaporn Promteangtrong, Anchisa Kunawudhi, Peerapon Kiatkittikul, Natphimol Boonkawin, Sukanya Yaset, Sirinsuda Somboon, Chanisa Chotipanich
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2024-10-01
Series:Indian Journal of Radiology and Imaging
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1779634
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author Dheeratama Siripongsatian
Attapon Jantarato
Chetsadaporn Promteangtrong
Anchisa Kunawudhi
Peerapon Kiatkittikul
Natphimol Boonkawin
Sukanya Yaset
Sirinsuda Somboon
Chanisa Chotipanich
author_facet Dheeratama Siripongsatian
Attapon Jantarato
Chetsadaporn Promteangtrong
Anchisa Kunawudhi
Peerapon Kiatkittikul
Natphimol Boonkawin
Sukanya Yaset
Sirinsuda Somboon
Chanisa Chotipanich
author_sort Dheeratama Siripongsatian
collection DOAJ
description Objective [177Lu]Lu-prostate-specific membrane antigen (PSMA)-617 radioligand therapy (RLT) shows promise for metastatic castration-resistant prostate cancer (mCRPC) patients with positive PSMA positron emission tomography (PET) imaging. Identifying high-risk patients is crucial. We evaluated pretherapeutic PSMA PET-derived parameters to predict prostate-specific antigen (PSA) response in patients undergoing [177Lu]Lu-PSMA-617 RLT.
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spelling doaj.art-cfbdec4d3c9e4966b21c1811fc8c80f42024-09-23T22:31:09ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Radiology and Imaging0971-30261998-38082024-10-01340457958710.1055/s-0044-1779634Pretherapeutic PSMA PET-Derived Semiquantitative Parameters as Predictors of PSA Response in Patients with mCRPC Receiving [<sup>177</sup>Lu]Lu-PSMA-617 Radioligand TherapyDheeratama Siripongsatian0https://orcid.org/0000-0001-7914-7141Attapon Jantarato1Chetsadaporn Promteangtrong2Anchisa Kunawudhi3Peerapon Kiatkittikul4Natphimol Boonkawin5Sukanya Yaset6Sirinsuda Somboon7Chanisa Chotipanich8National Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, ThailandNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, ThailandNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, ThailandNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, ThailandNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, ThailandNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, ThailandNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, ThailandNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, ThailandNational Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, Thailand Objective [177Lu]Lu-prostate-specific membrane antigen (PSMA)-617 radioligand therapy (RLT) shows promise for metastatic castration-resistant prostate cancer (mCRPC) patients with positive PSMA positron emission tomography (PET) imaging. Identifying high-risk patients is crucial. We evaluated pretherapeutic PSMA PET-derived parameters to predict prostate-specific antigen (PSA) response in patients undergoing [177Lu]Lu-PSMA-617 RLT.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1779634pretherapeutic PSMA PETmetastatic castration-resistant prostate cancerliver metastasis[177Lu]Lu-PSMA-617radioligand therapy
spellingShingle Dheeratama Siripongsatian
Attapon Jantarato
Chetsadaporn Promteangtrong
Anchisa Kunawudhi
Peerapon Kiatkittikul
Natphimol Boonkawin
Sukanya Yaset
Sirinsuda Somboon
Chanisa Chotipanich
Pretherapeutic PSMA PET-Derived Semiquantitative Parameters as Predictors of PSA Response in Patients with mCRPC Receiving [<sup>177</sup>Lu]Lu-PSMA-617 Radioligand Therapy
Indian Journal of Radiology and Imaging
pretherapeutic PSMA PET
metastatic castration-resistant prostate cancer
liver metastasis
[177Lu]Lu-PSMA-617
radioligand therapy
title Pretherapeutic PSMA PET-Derived Semiquantitative Parameters as Predictors of PSA Response in Patients with mCRPC Receiving [<sup>177</sup>Lu]Lu-PSMA-617 Radioligand Therapy
title_full Pretherapeutic PSMA PET-Derived Semiquantitative Parameters as Predictors of PSA Response in Patients with mCRPC Receiving [<sup>177</sup>Lu]Lu-PSMA-617 Radioligand Therapy
title_fullStr Pretherapeutic PSMA PET-Derived Semiquantitative Parameters as Predictors of PSA Response in Patients with mCRPC Receiving [<sup>177</sup>Lu]Lu-PSMA-617 Radioligand Therapy
title_full_unstemmed Pretherapeutic PSMA PET-Derived Semiquantitative Parameters as Predictors of PSA Response in Patients with mCRPC Receiving [<sup>177</sup>Lu]Lu-PSMA-617 Radioligand Therapy
title_short Pretherapeutic PSMA PET-Derived Semiquantitative Parameters as Predictors of PSA Response in Patients with mCRPC Receiving [<sup>177</sup>Lu]Lu-PSMA-617 Radioligand Therapy
title_sort pretherapeutic psma pet derived semiquantitative parameters as predictors of psa response in patients with mcrpc receiving sup 177 sup lu lu psma 617 radioligand therapy
topic pretherapeutic PSMA PET
metastatic castration-resistant prostate cancer
liver metastasis
[177Lu]Lu-PSMA-617
radioligand therapy
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1779634
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