Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategies

Urinary tract infections (UTIs) are one of the most important causes of morbidity and health care spending affecting persons of all ages. Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. UTIs associated with microbial biofi...

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Main Authors: Cristina Delcaru, Ionela Alexandru, Paulina Podgoreanu, Mirela Grosu, Elisabeth Stavropoulos, Mariana Carmen Chifiriuc, Veronica Lazar
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/5/4/65
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author Cristina Delcaru
Ionela Alexandru
Paulina Podgoreanu
Mirela Grosu
Elisabeth Stavropoulos
Mariana Carmen Chifiriuc
Veronica Lazar
author_facet Cristina Delcaru
Ionela Alexandru
Paulina Podgoreanu
Mirela Grosu
Elisabeth Stavropoulos
Mariana Carmen Chifiriuc
Veronica Lazar
author_sort Cristina Delcaru
collection DOAJ
description Urinary tract infections (UTIs) are one of the most important causes of morbidity and health care spending affecting persons of all ages. Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. UTIs associated with microbial biofilms developed on catheters account for a high percentage of all nosocomial infections and are the most common source of Gram-negative bacteremia in hospitalized patients. The purpose of this mini-review is to present the role of microbial biofilms in the etiology of female UTI and different male prostatitis syndromes, their consequences, as well as the challenges for therapy
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spelling doaj.art-cfc60e008e10459db5c4bbae3e99f7552022-12-22T04:10:35ZengMDPI AGPathogens2076-08172016-11-01546510.3390/pathogens5040065pathogens5040065Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategiesCristina Delcaru0Ionela Alexandru1Paulina Podgoreanu2Mirela Grosu3Elisabeth Stavropoulos4Mariana Carmen Chifiriuc5Veronica Lazar6Earth, Environmental and Life Sciences Section-ICUB, Research Institute of the University of Bucharest, University of Bucharest, Bucharest 060101, RomaniaIancului Private Laboratory, Bucharest 060101, RomaniaIancului Private Laboratory, Bucharest 060101, RomaniaDepartment of Microbiology & Immunology, Faculty of Biology, University of Bucharest, Bucharest 060101, RomaniaEarth, Environmental and Life Sciences Section-ICUB, Research Institute of the University of Bucharest, University of Bucharest, Bucharest 060101, RomaniaEarth, Environmental and Life Sciences Section-ICUB, Research Institute of the University of Bucharest, University of Bucharest, Bucharest 060101, RomaniaEarth, Environmental and Life Sciences Section-ICUB, Research Institute of the University of Bucharest, University of Bucharest, Bucharest 060101, RomaniaUrinary tract infections (UTIs) are one of the most important causes of morbidity and health care spending affecting persons of all ages. Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. UTIs associated with microbial biofilms developed on catheters account for a high percentage of all nosocomial infections and are the most common source of Gram-negative bacteremia in hospitalized patients. The purpose of this mini-review is to present the role of microbial biofilms in the etiology of female UTI and different male prostatitis syndromes, their consequences, as well as the challenges for therapyhttp://www.mdpi.com/2076-0817/5/4/65UPEC 1quorum sensing (QS) 2antibiofilm 3
spellingShingle Cristina Delcaru
Ionela Alexandru
Paulina Podgoreanu
Mirela Grosu
Elisabeth Stavropoulos
Mariana Carmen Chifiriuc
Veronica Lazar
Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategies
Pathogens
UPEC 1
quorum sensing (QS) 2
antibiofilm 3
title Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategies
title_full Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategies
title_fullStr Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategies
title_full_unstemmed Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategies
title_short Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategies
title_sort microbial biofilms in urinary tract infections and prostatitis etiology pathogenicity and combating strategies
topic UPEC 1
quorum sensing (QS) 2
antibiofilm 3
url http://www.mdpi.com/2076-0817/5/4/65
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