MTS1338, A Small Mycobacterium tuberculosis RNA, Regulates Transcriptional Shifts Consistent With Bacterial Adaptation for Entering Into Dormancy and Survival Within Host Macrophages

MTS1338, A Small Mycobacterium tuberculosis RNA, Regulates Transcriptional Shifts Consistent With Bacterial Adaptation for Entering Into Dormancy and Survival Within Host Macrophages

Small non-coding RNAs play a significant role in bacterial adaptation to changing environmental conditions. We investigated the dynamics of expression of MTS1338, a small non-coding RNA of Mycobacterium tuberculosis, in the mouse model in vivo, regulation of its expression in the infected macrophage...

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Bibliographic Details
Main Authors: Elena G. Salina, Artem Grigorov, Yulia Skvortsova, Konstantin Majorov, Oksana Bychenko, Albina Ostrik, Nadezhda Logunova, Dmitriy Ignatov, Arseny Kaprelyants, Alexander Apt, Tatyana Azhikina
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Mycobacterium tuberculosis
tuberculosis
small RNA MTS1338
RNA-seq
infection
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00405/full

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