Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantifying Fentanyl and 22 Analogs and Metabolites in Whole Blood, Urine, and Hair

Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantifying Fentanyl and 22 Analogs and Metabolites in Whole Blood, Urine, and Hair

Recently, synthetic opioid-related overdose fatalities, led by illicitly manufactured fentanyl and analogs, increased at an alarming rate, posing a global public health threat. New synthetic fentanyl analogs have been constantly emerging onto the drug marked for the last few years, to circumvent the...

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Bibliographic Details
Main Authors: Francesco Paolo Busardò, Jeremy Carlier, Raffaele Giorgetti, Adriano Tagliabracci, Roberta Pacifici, Massimo Gottardi, Simona Pichini
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Chemistry
Subjects:
fentanyl
fentanyl analogs
UHPLC-MS/MS
blood
urine
hair
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00184/full

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