<named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Reduces SUMOylation To Limit Host Defense Responses

<named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Reduces SUMOylation To Limit Host Defense Responses

ABSTRACT Klebsiella pneumoniae is an important cause of multidrug-resistant infections worldwide. Understanding the virulence mechanisms of K. pneumoniae is a priority and timely to design new therapeutics. Here, we demonstrate that K. pneumoniae limits the SUMOylation of host proteins in epithelial...

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Bibliographic Details
Main Authors: Joana Sá-Pessoa, Kornelia Przybyszewska, Filipe Nuno Vasconcelos, Amy Dumigan, Christian G. Frank, Laura Hobley, Jose A. Bengoechea
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mBio
Subjects:
Klebsiella pneumoniae
SUMOylation
let-7
SENP2
interferon
NEDDylation
Online Access:https://journals.asm.org/doi/10.1128/mBio.01733-20

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